Electron microscopic examination of Aedes albopictus clone C6/36 cells infected with dengue virus 2 at elevated incubation temperature.

摘要

Morphological changes such as loss of cytoplasm, membrane destruction and vacuolar swelling in A. albopictus C6/36 cells infected with dengue virus 2 New Guinea B strain and incubated at 28deg C and 37deg C, were observed under electron microscopy. Both infected and uninfected cells showed significant damage at 37deg C, in contrast to a normal appearance at 28deg C. A higher number of virus particles were observed in the cytoplasm at 37deg C than at 28deg C.