Efficacy and safety of tapentadol prolonged release for moderate-to-severe chronic osteoarthritis knee pain: a pooled analysis of two double-blind, randomized, placebo- and oxycodone controlled release-controlled studies

Lange Bernd; von Zabern Detlef; Elling Christian; Dubois Cecile

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Efficacy and safety of tapentadol prolonged release for moderate-to-severe chronic osteoarthritis knee pain: a pooled analysis of two double-blind, randomized, placebo- and oxycodone controlled release-controlled studies

机译：Tabentadol的疗效和安全性延长释放中度至严重的慢性骨关节炎膝关节疼痛：两种双盲，随机，安慰剂和羟考酮控制释放控制研究的合并分析

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Objective: To compare efficacy and safety of tapentadol prolonged-release (PR) and oxycodone-controlled release (CR) in moderate-to-severe chronic osteoarthritis knee pain.

机译：目的：比较Tabentadol延长释放（PR）和羟考酮控制释放（Cr）在中度至重度慢性骨关节炎膝关节疼痛中的疗效和安全性。

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来源
《Current medical research and opinion》 |2017年第8期|共10页
作者
Lange Bernd; von Zabern Detlef; Elling Christian; Dubois Cecile;
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作者单位

Grunenthal GmbH Zieglerstr 6 D-52078 Aachen Germany;

Grunenthal GmbH Zieglerstr 6 D-52078 Aachen Germany;

Grunenthal GmbH Zieglerstr 6 D-52078 Aachen Germany;

Grunenthal GmbH Zieglerstr 6 D-52078 Aachen Germany;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
Chronic osteoarthritis pain; Tapentadol PR; Oxycodone CR; Pain relief; Quality-of-life; Functionality;

机译：慢性骨关节炎疼痛;Tapentadol Pr;羟考酮Cr;疼痛缓解;生活质量;功能;

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2. Efficacy and safety of tapentadol prolonged release for moderate-to-severe chronic osteoarthritis knee pain: a pooled analysis of two double-blind, randomized, placebo- and oxycodone controlled release-controlled studies [J] . Lange Bernd, von Zabern Detlef, Elling Christian, Current medical research and opinion . 2017,第8期

机译：Tabentadol的疗效和安全性延长释放中度至严重的慢性骨关节炎膝关节疼痛：两种双盲，随机，安慰剂和羟考酮控制释放控制研究的合并分析
3. Tapentadol prolonged-release for moderate-to-severe chronic osteoarthritis knee pain: a double-blind, randomized, placebo- and oxycodone controlled release-controlled study [J] . Serrie Alain, Lange Bernd, Steup Achim Current medical research and opinion . 2017,第8期

机译：Tapentadol延长 - 释放中度至严重的慢性骨关节炎膝关节疼痛：双盲，随机，安慰剂和羟考酮控制释放控制研究
4. Efficacy and safety of tapentadol prolonged release formulation in the treatment of elderly patients with moderate-to-severe chronic osteoarthritis knee pain: a pooled analysis of two double-blind, randomized, placebo-, and active-controlled trials [J] . Lange Bernd, Sohns Melanie, Tempero Jose, Current medical research and opinion . 2018,第12期

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6. Body schema acuity training and FeldenkraisRTM movements compared to core stabilization biofeedback and motor control exercises: Comparative effects on chronic non-specific low back pain in an outpatient clinical setting: A randomized controlled comparative efficacy study. [D] . Sobie, Timothy J. 2016

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7. Efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of moderate/severe chronic non-malignant pain: results of a prospectively designed pooled analysis of two randomised double-blind clinical trials [O] . Oliver Löwenstein, Petra Leyendecker, Eberhard A Lux, 2010

机译：缓释羟考酮和纳洛酮联合治疗中度/重度慢性非恶性疼痛的疗效和安全性：两项随机双盲临床试验的前瞻性汇总分析结果
8. PMS4 EUROQOL-5 DIMENSION HEALTH STATUS QUESTIONNAIRE RESULTS FROM A RANDOMIZED, DOUBLE-BLIND, PLACEBO- AND ACTIVE-CONTROLLED PHASE 3 STUDY OF TAPENTADOL EXTENDED RELEASE (ER) FOR THE MANAGEMENT OF CHRONIC OSTEOARTHRITIS KNEE PAIN [O] . Kavanagh S, Ashworth J, Lange B, 2009

机译：PMS4 EUROQOL-5维健康状况问卷调查来自于随机，双盲，放置和主动控制的阶段3研究塔彭多醇延长释放（ER）用于管理慢性骨关节炎膝痛的研究

Efficacy and safety of tapentadol prolonged release for moderate-to-severe chronic osteoarthritis knee pain: a pooled analysis of two double-blind, randomized, placebo- and oxycodone controlled release-controlled studies

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