Study of Efficacy and Safety of Willow Bark Extract (Assalix) in Treatment of Chronic Low Back Pain in Patients of Different Age with Osteochondrosis

摘要

Phytotherapy with a low level of toxicity and low incidence of adverse events is very popular today. Assalix is a standardized willow bark extract having analgesic and anti-inflammatory action. The aim of the study was to estimate the efficacy and safety of Assalix in long-term treatment of chronic low back pain (LBP) syndrome in patients of different age. 16 patients aged 30-74 years were examined. Evaluation of pain syndrome and vital activity were performed by the Roland-Morris and Mc-Gill questionnaires, VAS and Euro-Qol scale. All patients took Assalix in a dose of 2 dragees twice a day during 20 days, afterwards - 1 dragee twice a day during the next 20 days. After the course of treatment with Assalix the reliable decline of LBP syndrome intensity, significant improvement of spine functional state indexes and of the quality of life were found. Thus, Assalix is effective and safe in decreasing of the LBP syndrome pronouncement in patients of different age-dependent groups.