Tm-170-EDTMP A Prospective Alternative of (SrCl2)-Sr-89 for Theranostic Treatment of Metastatic Bone Pain

摘要

We have earlier reported the potential of(170) Tm-EDTMP as an alternative cost-effective radiopharmaceutical of (SrCl2)-Sr-89 for bone pain palliation application. Encouraging results obtained in the radiochemical studies and biological evaluations in animal model have prompted us to initiate the clinical study to evaluate the potential of Tm-170-EDTMP in human cancer patients. The serial scintigraphic images represent the whole-body scans of a patient (68 years old woman) with skeletal metastases of carcinoma of the breast origin recorded after administering 370 MBq (10 mCi) of Tm-170-EDTMP at different post-administration time points along with the pre-therapy image recorded with (TC)-T-99m-MDP in the same patient