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首页> 外文期刊>Clinical cancer research: an official journal of the American Association for Cancer Research >Detection of Driver and Resistance Mutations in Leptomeningeal Metastases of NSCLC by Next-Generation Sequencing of Cerebrospinal Fluid Circulating Tumor Cells
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Detection of Driver and Resistance Mutations in Leptomeningeal Metastases of NSCLC by Next-Generation Sequencing of Cerebrospinal Fluid Circulating Tumor Cells

机译：下一代脑脊液循环肿瘤细胞下一代测序检测NSCLC叶片培养转移的驾驶员和电阻突变

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摘要

Purpose: Leptomeningeal metastases are more common in non-small cell lung cancer (NSCLC) with EGFR mutations. The diagnosis is difficult by traditional imaging only, and leads to poor understanding of resistance mechanisms of leptomeningeal metastases.
机译：目的：具有EGFR突变的非小细胞肺癌（NSCLC）中的髓质雌性转移更常见。 仅通过传统成像诊断难以理解，并导致易受乳化型转移抗性机制的理解。

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  • 作者

    Jiang Ben-Yuan; Li Yang-Si; Guo Wei-Bang; Zhang Xu-Chao; Chen Zhi-Hong; Su Jian; Zhong Wen-Zhao; Yang Xue-Ning; Yang Jin-Ji; Shao Yang; Huang Biao; Liu Yan-Hui; Zhou Qing; Tu Hai-Yan; Chen Hua-Jun; Wang Zhen; Xu Chong-Rui; Wang Bin-Chao; Wu Shu-Yu; Gao Cun-Yi; Zhang Xian; Wu Yi-Long;

  • 作者单位

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Geneseeq Biotechnol Inc Nanjing Jiangsu Peoples R China;

    Guangdong Acad Med Sci 106 Zhongshan Er Rd Guangzhou 510080 Guangdong Peoples R China;

    Guangdong Acad Med Sci 106 Zhongshan Er Rd Guangzhou 510080 Guangdong Peoples R China;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

    Geneseeq Biotechnol Inc Nanjing Jiangsu Peoples R China;

    Geneseeq Biotechnol Inc Nanjing Jiangsu Peoples R China;

    Geneseeq Biotechnol Inc Nanjing Jiangsu Peoples R China;

    Guangdong Gen Hosp Guangdong Lung Canc Inst Guangdong Prov Key Lab Translat Med Lung Canc;

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  • 正文语种 eng
  • 中图分类 肿瘤学;
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