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首页> 外文期刊>Clinical cancer research: an official journal of the American Association for Cancer Research >Clinical Significance of Four Molecular Subtypes of Gastric Cancer Identified by The Cancer Genome Atlas Project
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Clinical Significance of Four Molecular Subtypes of Gastric Cancer Identified by The Cancer Genome Atlas Project

机译:癌症基因组地图集项目鉴定的四种分子亚型的临床意义

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摘要

Purpose: The Cancer Genome Atlas (TCGA) project recently uncovered four molecular subtypes of gastric cancer: Epstein-Barr virus (EBV), microsatellite instability (MSI), genomically stable (GS), and chromosomal instability (CIN). However, their clinical significances are currently unknown. We aimed to investigate the relationship between subtypes and prognosis of patients with gastric cancer.
机译:目的:癌症基因组地图集(TCGA)项目最近未发现胃癌的四种分子亚型:Epstein-Barr病毒(EBV),微卫星不稳定性(MSI),基因组稳定(GS)和染色体不稳定性(CIN)。 然而,他们目前未知的临床意义。 我们旨在探讨胃癌患者亚型和预后的关系。

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    Univ Texas MD Anderson Canc Ctr Dept Syst Biol Houston TX 77030 USA;

    Chonnam Natl Univ Dept Hematol Oncol Sch Med Gwangju South Korea;

    Univ Texas MD Anderson Canc Ctr Dept Syst Biol Houston TX 77030 USA;

    Baylor Coll Med Michael E DeBakey Dept Surg Div Thorac Surg Houston TX 77030 USA;

    Korea Univ Coll Med Med Ctr Dept Internal Med Div Hematooncol Seoul South Korea;

    Kyung Hee Univ Sch Med Dept Internal Med Seoul South Korea;

    Seoul Natl Univ Coll Med Bundang Hosp Dept Internal Med Seongnam South Korea;

    Univ Texas MD Anderson Canc Ctr Dept Syst Biol Houston TX 77030 USA;

    Univ Texas MD Anderson Canc Ctr Dept Syst Biol Houston TX 77030 USA;

    Kosin Univ Coll Med Dept Surg Busan South Korea;

    Yonsei Univ Coll Med Dept Surg Seoul South Korea;

    Ewha Womans Univ Res Ctr Cellular Homeostasis Dept Life Sci Seoul South Korea;

    Yonsei Univ Coll Med Dept Med Oncol Seoul South Korea;

    Univ Texas MD Anderson Canc Ctr Dept Syst Biol Houston TX 77030 USA;

    Kyung Hee Univ Sch Med Dept Obstet &

    Gynaecol Kyung Hee Univ Hosp Seoul South Korea;

    Samsung Med Ctr Div Hematol Oncol Dept Med Seoul South Korea;

    Samsung Med Ctr Div Hematol Oncol Dept Med Seoul South Korea;

    Samsung Med Ctr Dept Surg Seoul South Korea;

    Yonsei Univ Coll Med Dept Surg Seoul South Korea;

    Univ Texas MD Anderson Canc Ctr Dept Gastrointestinal Med Oncol Houston TX 77030 USA;

    Univ Texas MD Anderson Canc Ctr Dept Syst Biol Houston TX 77030 USA;

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  • 正文语种 eng
  • 中图分类 肿瘤学;
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