NON-INVASIVE BLOOD GLUCOSE ANALYSIS BASED ON GALVANIC SKIN RESPONSE FOR DIABETIC PATIENTS

摘要

Diabetes is a chronic disease due to the lack of production of hormone insulin by the beta cells in the islets of Langerhans. Many diabetic patients often draw a small amount of blood to measure the glucose level every day. This vital information is needed to control their daily food intake. One such method could cause infection and discomfort to the patient. Non-invasive glucose measurement techniques overcome these challenges to monitor blood glucose level continuously. The aim and objective of this study are as follows: (i) to correlate the skin resistance based on Galvanic skin response (GSR) and blood glucose level for diabetic and non-diabetic subject and (ii) to estimate the blood glucose value based on GSR voltage and resistance using stepwise linear regression model. About 50 diabetic and 50 non-diabetic subjects were included in this study. Blood glucose level is recorded using the minimally invasive device called accu-chek for all the subjects. GSR resistance and GSR voltage were recorded using the designed instrumentation setup. In diabetic subjects, the measured blood glucose level shows negative correlation with the GSR voltage (r=?0.319, p<0.01) and GSR resistance (r=?0.323, p<0.01). The estimated blood glucose level can be predicted with good sensitivity (94%) and accuracy (92%) using age and GSR voltage, or by the combination of age and GSR resistance in the evaluation of diabetic subjects.