Safety and efficacy of nivolumab for metastatic renal cell carcinoma: real-world results from an expanded access programme

De Giorgi Ugo; Carteni Giacomo; Giannarelli Diana; Basso Umberto; Galli Luca; Cortesi Enrico; Caserta Claudia; Pignata Sandro; Sabbatini Roberto; Bearz Alessandra; Buti Sebastiano; Lo Re Giovanni; Berruti Alfredo; Bracarda Sergio; Cognetti Francesco; Rastelli Francesca; Fornarini Giuseppe; Porta Camillo; Turci Daniele; Sternberg Cora N.; Procopio Giuseppe; Falcone A.; Roila F.; Cascinu S.; Tirelli U.; Giustini L.; Sobrero A.; Cappuzzo F.; Tortora G.; Tassinari D.; Passalacqua R.; Pazzola A.; Surico G.; Maio M.; Benedetti G.; Barone C.; Adamo V.; Ricevuto E.; De Censi A.; Spada M.; Tonini G.; Pinto C.; Ciuffreda L.; Ruggeri E. M.; Bengala C.; Scotti V.; Fagnani D.; Bonetti A.; Mitterer M.; Castiglione F.; Bidoli P.; Ferrau F.; Crino L.; Frassoldati A.; Marchetti P.; Mini E.; Scoppola A.; Verusio C.; Favaretto A.; Di Costanzo F.; Fasola G.; Merlano M.; Artioli F.; Di Leo A.; Romito S.; Maestri A.; Giorgio C. Giannitto; Ionta M. T.; Verderame F.; Zampa G.; Numico G.; Minelli M.; Tagliaferri P.; Foa P.; Palmiotti G.; De Placido S.; Mattioli R.; Iuliano F.; Defraia E.; Siena S.; Clerico M.; Salvagno L.; Ceresoli G. L.; Bernardo A.; Di Lieto M.; Moroni M.; Maisano M.; Scartozzi M.; Scagliotti G.; Soraru M.; Pepe S.; Scaltriti A.; Gebbia V.; Testa E.; Lorusso V.; Bordonaro R.; De Signoribus G.; Tedde N.; Santoro A.; Francini G.; Aondio G.

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Safety and efficacy of nivolumab for metastatic renal cell carcinoma: real-world results from an expanded access programme

机译：Nivolumab对转移性肾细胞癌的安全性和有效性：展开进入计划的现实世界

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摘要

ObjectiveTo report the safety and efficacy results of patients enrolled in the Italian Nivolumab Renal Cell Cancer Expanded Access Programme.

机译：ObjectiveTo报告患者患有意大利Nivolumab肾细胞癌的患者的安全性和疗效结果。

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来源
《BJU international》 |2019年第1期|共8页
作者
De Giorgi Ugo; Carteni Giacomo; Giannarelli Diana; Basso Umberto; Galli Luca; Cortesi Enrico; Caserta Claudia; Pignata Sandro; Sabbatini Roberto; Bearz Alessandra; Buti Sebastiano; Lo Re Giovanni; Berruti Alfredo; Bracarda Sergio; Cognetti Francesco; Rastelli Francesca; Fornarini Giuseppe; Porta Camillo; Turci Daniele; Sternberg Cora N.; Procopio Giuseppe; Falcone A.; Roila F.; Cascinu S.; Tirelli U.; Giustini L.; Sobrero A.; Cappuzzo F.; Tortora G.; Tassinari D.; Passalacqua R.; Pazzola A.; Surico G.; Maio M.; Benedetti G.; Barone C.; Adamo V.; Ricevuto E.; De Censi A.; Spada M.; Tonini G.; Pinto C.; Ciuffreda L.; Ruggeri E. M.; Bengala C.; Scotti V.; Fagnani D.; Bonetti A.; Mitterer M.; Castiglione F.; Bidoli P.; Ferrau F.; Crino L.; Frassoldati A.; Marchetti P.; Mini E.; Scoppola A.; Verusio C.; Favaretto A.; Di Costanzo F.; Fasola G.; Merlano M.; Artioli F.; Di Leo A.; Romito S.; Maestri A.; Giorgio C. Giannitto; Ionta M. T.; Verderame F.; Zampa G.; Numico G.; Minelli M.; Tagliaferri P.; Foa P.; Palmiotti G.; De Placido S.; Mattioli R.; Iuliano F.; Defraia E.; Siena S.; Clerico M.; Salvagno L.; Ceresoli G. L.; Bernardo A.; Di Lieto M.; Moroni M.; Maisano M.; Scartozzi M.; Scagliotti G.; Soraru M.; Pepe S.; Scaltriti A.; Gebbia V.; Testa E.; Lorusso V.; Bordonaro R.; De Signoribus G.; Tedde N.; Santoro A.; Francini G.; Aondio G.;
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作者单位

Ist Sci Romagnolo Studio &

Cura Tumori IRST IRCCS Dept Med Oncol Via Maroncelli 40 I-47014;

Azienda Osped Univ A Cardarelli Dept Med Oncol Naples Italy;

Regina Elena Natl Canc Inst IRCCS Dept Stat Rome Italy;

Ist Oncol Veneto IOV IRCCS Dept Clin &

Expt Oncol Med Oncol Unit 1 Padua Italy;

Azienda Osped Univ Pisana Spedali Riuniti S Chiar Dept Med Oncol Pisa Italy;

Policlin Umberto 1 Dept Med Oncol Rome Italy;

Azienda Osped Univ Santa Maria Dept Med Oncol Terni Italy;

Ist Nazl Tumori IRCCS Fdn G Pascale Dept Urogynaecol Oncol Naples Italy;

Azienda Osped Univ Policlin Modena Dept Hematol &

Oncol Modena Italy;

Ist Nazl Tumori IRCCS Dept Med Oncol Aviano Italy;

Azienda Osped Univ Parma Med Oncol Unit Parma Italy;

CRO IRCCS Dept Med Oncol CRO Pordenone S Vito Oncol Aviano Italy;

ASST Spedali Civili Brescia Dept Med Oncol Brescia Italy;

Azienda USL 8 Dept Med Oncol Arezzo Italy;

Regina Elena Natl Canc Inst IRCCS Dept Med Oncol Rome Italy;

Fermo Area Vasta 4 Dept Med Oncol Fermo Italy;

Azienda Osped Univ San Martino IST IRCCS Dept Med Oncol Genoa Italy;

Univ Pavia Pavia Italy;

Osped Santa Maria delle Croci Dept Med Oncol Ravenna Italy;

San Camillo Forlanini Hosp Dept Med Oncol Rome Italy;

Ist Nazl Tumori IRCCS Dept Med Oncol Milan Italy;

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原文格式 PDF
正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
关键词
renal cell cancer; nivolumab; expanded access programme; real-world experience;

机译：肾细胞癌;Nivolumab;扩展访问计划;现实世界经验;

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专利

1. 索拉非尼与舒尼替尼一线治疗中国转移性肾细胞癌患者的疗效、安全性和生活质量的比较 [J] . Wen Cai, Wen Kong, Baijun Dong, 癌症（英文版） . 2018,第003期
2. Safety and efficacy of nivolumab for metastatic renal cell carcinoma: real-world results from an expanded access programme [J] . De Giorgi Ugo, Carteni Giacomo, Giannarelli Diana, BJU international . 2019,第1期

机译：Nivolumab对转移性肾细胞癌的安全性和有效性：展开进入计划的现实世界
3. Safety and Efficacy of Cabozantinib for Metastatic Nonclear Renal Cell Carcinoma Real-world Data From an Italian Managed Access Program [J] . Prisciandaro Michele, Ratta Raffaele, Massari Francesco, American Journal of Clinical Oncology: Cancer Clinical Trials . 2019,第1期

机译：Cabozantib对意大利管理访问计划的转移性肾细胞癌现实世界数据的安全性和有效性
4. Safety and Efficacy of Cabozantinib for Metastatic Nonclear Renal Cell Carcinoma: Real-world Data From an Italian Managed Access Program (vol 42, pg 42, 2019) [J] . Prisciandaro M., Ratta R., Massari F. American Journal of Clinical Oncology: Cancer Clinical Trials . 2019,第4期

机译：Cabozantib对转移性否肾细胞癌的安全性和有效性：意大利管理访问计划的现实数据（第42卷42,2019）
5. When to Treat Metastatic Renal Cell Carcinoma Comorbidities, Systemic Therapy, and Active Surveillance in Metastatic Kidney Cancer [C] . Brian I. Rini Genitourinary Cancers Symposium . 2012

机译：何时治疗转移性肾细胞癌的组合，全身治疗，以及在转移性肾癌中的活跃监测
6. Methodological Approaches for Conducting Claims-Based Studies in Patients Diagnosed with Metastatic Renal Cell Carcinoma [D] . Chun, Danielle S. 2021

机译：用于诊断转移性肾细胞癌的患者的基于权利要求的基于权利要求的方法论方法
7. Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma and association between immune-related adverse events and survival: the Italian expanded access program [O] . Elena Verzoni, Giacomo Cartenì, Enrico Cortesi, 2019

机译：尼古鲁单抗在先前治疗的转移性肾细胞癌中的真实疗效和安全性以及免疫相关不良事件和生存之间的关联：意大利扩展准入计划
8. Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: the Italian expanded access program [O] . Elena Verzoni, Giacomo Cartenì, Enrico Cortesi, 2019

机译：在前治疗的转移性肾细胞癌中的现实世界疗效和安全性，免疫相关不良事件与生存之间的关联：意大利扩大访问计划

Safety and efficacy of nivolumab for metastatic renal cell carcinoma: real-world results from an expanded access programme

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