A bioactive terpenoid from the leaves of Callicarpa macrophyllaahl

摘要

From the chloroform extract of the leaves of Callicarpa macrophylla Vahl (Family:- Verbenaceae) two tetracyclic diterpene viz. calliterpenone and its monoacetate were isolated and their structures and stereochemistry were established by & "C NMRhhhhh spectroscopies. Plant Callicarpa macrophylla Vahl. (Family: Verbenaceae) is an important less known medicinal plant of the lower warm valleys of the Himalaya and is commonly known as Priyangoo or Daya. It is a perennial, deciduous shrub attaining 2.5mt. in hight. Essential oil obtained from different parts of Priyangoo through steam distillation ,revealed oil content in young leaves and tender stem , panicles and seeds while no essential oil content was observed in the roots. All The parts are important and are used to cure many diseases. The bark is used to heal cut and wounds. Seeds and roots are used for digestion and leaves are used in rheumatism. The fruits are used for blisters and boils. Various extract of this plant have shown anti-inflammatory, antifungal and antibacterial activities.