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机译:基于结构的6-氯-4-氨基喹唑啉-2-甲酰胺衍生物的设计为有效和选择性P21-活化激酶4(PAK4)抑制剂
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
Tsinghua-Peking Joint Center for Life Sciences Beijing Advanced Innovation Center for Structural Biology Department of Basic Medical Sciences School of Medicine Tsinghua University Beijing 100084 China;
Institute of Materials Research and Engineering A*STAR (Agency for Science Technology and Research) 2 Fusionopolis Way Innovis #08-03 Singapore 138634;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
Department of Cell Biology Key Laboratory of Cell Biology Ministry of Public Health and Key Laboratory of Medical Cell Biology Ministry of Education China Medical University Shenyang 110001 China;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
Department of Cell Biology Key Laboratory of Cell Biology Ministry of Public Health and Key Laboratory of Medical Cell Biology Ministry of Education China Medical University Shenyang 110001 China;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
Department of Cell Biology Key Laboratory of Cell Biology Ministry of Public Health and Key Laboratory of Medical Cell Biology Ministry of Education China Medical University Shenyang 110001 China;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
School of Pharmacy Shenyang Pharmaceutical University Shenyang 110016 China;
Tsinghua-Peking Joint Center for Life Sciences Beijing Advanced Innovation Center for Structural Biology Department of Basic Medical Sciences School of Medicine Tsinghua University Beijing 100084 China;
Department of Cell Biology Key Laboratory of Cell Biology Ministry of Public Health and Key Laboratory of Medical Cell Biology Ministry of Education China Medical University Shenyang 110001 China;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
Key Laboratory of Structure-Based Drug Design &
Discovery of Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 China;
机译:基于结构的6-氯-4-氨基喹唑啉-2-甲酰胺衍生物的设计为有效和选择性P21-活化激酶4(PAK4)抑制剂
机译:利用基于结构的药物设计发现丝裂原活化蛋白激酶相互作用激酶1和2(MNK1 / 2)的选择性和强效抑制剂。
机译:基于结构的10-DEBC衍生物优化,作为有效和选择性PIM-1激酶抑制剂
机译:以喹唑啉作为一般支持物来设计有效和选择性激酶抑制剂:在类似FMS的酪氨酸激酶3中的应用
机译:TAS05567,脾酪氨酸激酶的强效和选择性抑制剂,在炎症性疾病和B细胞恶性动物模型中的药理特性
机译:高选择性和有效的G蛋白偶联受体激酶2抑制剂的基于结构的设计合成和生物学评估
机译:基于结构的6-氯-4-氨基喹唑啉-2-甲酰胺衍生物的设计为有效和选择性P21-活化激酶4(PAK4)抑制剂
机译:基于结构的stromelysin-1和mr1-mmp有效和选择性抑制剂的设计