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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >A Pivotal Response Treatment Package for Children With Autism Spectrum Disorder: An RCT
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A Pivotal Response Treatment Package for Children With Autism Spectrum Disorder: An RCT

机译:用于自闭症谱系障碍儿童的枢轴反应治疗包:RCT

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OBJECTIVES:Our aim was to conduct a randomized controlled trial to evaluate a pivotal response treatment package (PRT-P) consisting of parent training and clinician-delivered in-home intervention on the communication skills of children with autism spectrum disorder.METHODS:Forty-eight children with autism spectrum disorder and significant language delay between 2 and 5 years old were randomly assigned to PRT-P (n = 24) or the delayed treatment group (n = 24) for 24 weeks. The effect of treatment on child communication skills was assessed via behavioral coding of parent-child interactions, standardized parent-report measures, and blinded clinician ratings.RESULTS:Analysis of child utterances during the structured laboratory observation revealed that, compared with the delayed treatment group, children in PRT-P demonstrated greater improvement in frequency of functional utterances (F-1,F-41 = 6.07; P = .026; d = 0.61). The majority of parents in the PRT-P group (91%) were able to implement pivotal response treatment (PRT) with fidelity within 24 weeks. Children receiving PRT-P also demonstrated greater improvement on the Brief Observation of Social Communication Change, on the Clinical Global Impressions Improvement subscale, and in number of words used on a parent-report questionnaire.CONCLUSIONS:This is the first 24-week randomized controlled trial in which community treatment is compared with the combination of parent training and clinician-delivered PRT. PRT-P was effective for improving child social communication skills and for teaching parents to implement PRT. Additional research will be needed to understand the optimal combination of treatment settings, intensity, and duration, and to identify child and parent characteristics associated with treatment response.
机译:目标:我们的宗旨是进行随机对照试验,以评估由父母培训和临床医生的枢轴反应治疗包(PRT-P) - 在自闭症谱系上的儿童的沟通技巧中提供的家庭干预。方法:四十 - 八个患有自闭症谱系障碍和2至5岁的显着语言延迟的儿童被随机分配给Prt-p(n = 24)或延迟治疗组(n = 24)24周。治疗儿童沟通技能的效果是通过行为的亲子互动编码,规范家长报告的措施进行评估,并蒙蔽医生ratings.RESULTS:孩子的话语分析结构化实验室观察时透露,与延迟治疗组相比, ,PRT-P中的儿童在功能性话语的频率(F-1,F-41 = 6.07; p = .026; d = 0.61)上显示出更大的改善。 PRT-P组大多数父母(91%)能够在24周内实施富翼的枢轴反应治疗(PRT)。接受PRT-P的儿童也表明了对社会沟通变革的简要观察,在临床全球展示次数改善子程中,以及在母公司报告问卷中使用的单词数量进行了更大的改进。结论:这是第一个24周随机控制与父母培训和临床医生交付的PRT的组合进行了比较了社区治疗的试验。 PRT-P有效地改善儿童社交沟通技巧,并为父母施行PRT。需要进行额外的研究以了解治疗环境,强度和持续时间的最佳组合,并识别与治疗响应相关的儿童和父母特征。

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