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Surgical Complications in 100 Donor Hepatectomies for Living Donor Liver Transplantation in a Single Brazilian Center

机译:在单个巴西中心进行100个供体肝切除术进行活体供肝移植的手术并发症

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The rising demand for liver transplantation has continued to outspace the availability of deceased donor organs, leading to the need for other treatment options including living donor liver transplantation (LDLT). A precise evaluation of surgical complications is the most important issue in this setting. There are controversies about donor morbidity with reports ranging from 13%-75%. The aim of this study was to retrospectively analyze 100 LDLTs performed in a single Brazilian center from December 2002 to August 2008, stratifying the complications according to Clavien's scoring system. None of the donors experienced life-threatening complications or died. The majority of donors (n = 74) did not suffer any complication. Twenty-eight complications were observed in 26 patients. Fifty-seven hepatectomies were performed for adult and 43 for pediatric transplantations. According to the Brisbane classifications, we performed 49 right and 2 left hepatectomies as well as 49 left lateral segmentectomies. According to Clavien, the complications were as follows: grade I (n = 11; 39.2%); grade II (n = 8; 28.5%); and grade III (n = 9; 32.3%). No patient presented with grade IV or V. The most common problem a biliary tract injury, similar to other series. In this Brazilian series, hepatectomy for LDLT was a safe procedure with low morbidity, regardless of the type of liver resection. This practice will probably continue to grow to alleviate the pressure of growing waiting lists.
机译:对肝移植的需求不断增长,已继续使已故的供体器官失去供应,从而导致需要其他治疗方案,包括活体供体肝移植(LDLT)。在这种情况下,对手术并发症的准确评估是最重要的问题。关于捐赠者发病率存在争议,报道范围为13%-75%。这项研究的目的是回顾性分析2002年12月至2008年8月在单个巴西中心进行的100次LDLT,根据Clavien的评分系统对并发症进行分层。没有一个捐助者经历过危及生命的并发症或死亡。大多数捐赠者(n = 74)没有任何并发​​症。在26例患者中观察到28例并发症。成人进行了57例肝切除术,儿科移植进行了43例肝切除术。根据布里斯班分类,我们进行了49个右肝切除术和2个左肝切除术以及49个左外侧节段切除术。根据克拉维恩的说法,并发症如下:I级(n = 11; 39.2%); I级(11%)。 II级(n = 8; 28.5%);三级(n = 9; 32.3%)。没有患者出现IV级或V级。最常见的问题是胆道损伤,与其他系列相似。在这个巴西系列文章中,不管肝切除的类型如何,LDLT肝切除术都是一种安全的方法,发病率低。这种做法可能会继续增长,以减轻等待名单增加的压力。

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