A rapid,solvent-free,ligandless and mild method for preparing aromatic ketones from acyl chlorides and arylboronic acids via a Suzuki-Miyaura type of coupling reaction

摘要

Aromatic ketones were synthesized via a palladium catalyzed cross-coupling reaction of boronic acids with acyl chlorides in the presence of Na_2CO_3 at room temperature under solvent-free conditions.The Iigand-free and mild reaction conditions,highly rapid reaction rate and good to excellent yields are important features of this method.