One-Pot Synthesis of 2-Amino-1,3-selenazole via an Intermediary Amidinoselenourea

摘要

Herein we describe a sequential one-pot multicomponent reaction for the synthesis of 2-amino-1,3-selenazole. Amidinoselenourea synthesized from isoselenocyanate and N,N-diethyl-amidine reacted with various halomethylene compounds to furnish 2-amino-1,3-selenazole derivatives in 65-89% yields. The molecular structure of the trisubstituted selenazole formed was unambiguously established by X-ray crystallography.