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Thermo Scientific HyClone Cell Boost Process Supplements Maximize Cell Culture Production and Performance

机译:Thermo Scientific HyClone细胞增强工艺补充剂可最大化细胞培养物的产量和性能

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摘要

Major drivers in biopharmaceutical development and manufacturing include improved performance in bioprocess cell culture through increased cell viability, product quality, and yield. Success has been achieved in addressing these drivers using Thermo Scientific HyClone Cell Boost by providing solutions that include strategic supplementation of nutrients based on metabolic profiling of cells and media at various stages of the bioprocessing cell culture campaign. One of the greatest improvements is derived from increased viable cell concentration and volumetric productivity. Today's experienced fed-batch bioreactor operators can expect more than 10 times the efficiencies possible as compared to a few years ago (1).
机译:生物制药开发和制造的主要推动力包括通过提高细胞活力,产品质量和产量来改善生物过程细胞培养的性能。通过使用Thermo Scientific HyClone Cell Boost提供解决方案,成功解决了这些驱动因素,这些解决方案包括在生物处理细胞培养活动的各个阶段基于细胞和培养基的代谢谱对战略营养物进行战略性补充。最大的改进之一来自增加的活细胞浓度和容积生产力。与几年前相比,当今经验丰富的分批补料生物反应器操作者可以期望的效率是其十倍以上(1)。

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