Compositions of matter, polipeptideo, sequence of DNA, the vehicle of expression and replicable, microorganism or cell culture, plasmideo extract, cell culture, cell culture transform.The use of human immune interferon mature process, the expression of a gene, process for production of a polipeptideo, process for production of a vehicle of expression, and product obtained by such processes.

摘要

Disclosed is a complete description of the preparation of a novel, substantially pure polypeptide via recombinant DNA techniques utilizing any of an assortment of expression vectors and host cultures. The polypeptide, human immune (gamma) interferon (IFN- gamma ), is isolated in substantially pure form and characterized in terms of DNA and amino acid sequences, physical attributes and biological activity.