Chemical Constituents from Maca (Lepidium meyenii)

摘要

Two new natural products, tetrahydro-2-benzyl-1H-pyrrolo-[1,2-C] imidazole-1,3(2H)-dione (1) and (1S,4R,4aR,9aS)-4a-methyl-1,4,4a, 9a- tetrahydro-1,4-methano-anthracene-9,10-dione (2), together with eleven known compounds (3-13) were isolated from the petroleum ether fraction of the 95% ethanol extract from the tubers of Lepidium meyenii. Among them, compounds 1 and 2 were new natural products, compounds 3, 4, 7-11, and 13 were isolated from L. meyenii for the first time. In addition, the spectroscopic data of compound 1 were firstly reported. Their structures were elucidated by 1D and 2D NMR spectroscopic analysis along with comparison with literature reports.