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Lepidium meyenii (Maca) reduces spermatogenic damage induced by a single dose of malathion in mice

机译:Mepienii(Maca)减少小鼠单次马拉硫磷引起的生精损伤

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摘要

Aim: To observe the effect of the aqueous extract of hypocotyls of the plant Lepidium meyenii (Maca) on spermatogenic damage induced by the organophosphate insecticide malathion in mice. Methods: Mice were treated with 80or 21 days after injection of the malathion. Stages of the seminiferous epithelium were assessed by transillumination on days 0, 7, 14 and 21. Results: The administration of Maca increased significantly the length of stage Ⅷ on days7, 14 and 21 of treatment compared with the controls. An increase in the length of stage Ⅸ occurred on day 14 of treatment. Malathion affected spermatogenesis by reducing the lengths of stage Ⅸ on day 7, stages Ⅶ and Ⅸ-Ⅺ on day 14 and a recovery of stages Ⅸ-Ⅻ on day 21. The magnitude of alteration in the length of stage Ⅸ produced by malathion was significantly reduced by Maca on days 7 and 14. The length of stage Ⅷ was increased when Maca was administered to mice treated with malathion. Assessment of the relative length of stages of the seminiferous epithelium showed that Maca treatment resulted in rapid recovery of the effect of malathion. Conclusion: Maca enhances spermatogenesis following spermatogenic damage caused by the organophosphorous pesticide.
机译:目的:观察Mepienii(Maca)植物下胚轴水提物对小鼠有机磷杀虫剂马拉硫磷所致生精损伤的作用。方法:在注射马拉硫磷后80或21天对小鼠进行治疗。通过透照在第0、7、14和21天评估生精上皮的阶段。结果:与对照组相比,施用Maca在治疗的第7、14和21天显着延长了stage期的长度。在治疗的第14天,增加了Ⅸ期的长度。马拉硫磷通过减少第7天的阶段stage的长度以及第14天的阶段Ⅶ和Ⅸ-Ⅺ的长度以及在第21天恢复阶段Ⅸ-Ⅻ来影响精子发生。马拉硫磷产生的阶段length长度变化的幅度显着在第7天和第14天被Maca降低。将Maca给予马拉硫磷治疗的小鼠时,Ⅷ期的长度增加了。对生精上皮的相对阶段长度的评估表明,Maca治疗可导致马拉硫磷的作用迅速恢复。结论:Maca增强了有机磷农药引起的生精损伤后的生精能力。

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  • 来源
    《亚洲男性学杂志(英文版)》 |2005年第1期|71-76|共6页
  • 作者单位

    Faculty of Medicine, University of Chile and Instituto de Investigaciones de la Altura and Faculty of Sciences and Philosophy,Universidad Peruana Cayetano Heredia, Lima, Peru;

    Faculty of Medicine, University of Chile and Instituto de Investigaciones de la Altura and Faculty of Sciences and Philosophy,Universidad Peruana Cayetano Heredia, Lima, Peru;

    Faculty of Medicine, University of Chile and Instituto de Investigaciones de la Altura and Faculty of Sciences and Philosophy,Universidad Peruana Cayetano Heredia, Lima, Peru;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 chi
  • 中图分类 基础医学;
  • 关键词

    malathion; spermatogenesis; Lepidium meyenii (Maca); mice; seminiferous epithelium stages;

    机译:malathion;精子发生;Lepidium meyenii(猕猴);小鼠;血液上皮阶段;
  • 入库时间 2022-08-19 03:40:48
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