Experience of dermatological problems presenting to a large adult haemato-oncological centre (King's College Hospital, London) indicates 10 main haematological malignancies of interest to dermatologists (Table 1). The skin complications may be conveniently classified as infective, paraneoplastic, autoimmune or infiltrative, or be the result of treatment. The haematological diagnosis is often already established before any skin signs emerge (eg leukaemia cutis), but in some cases skin lesions may be the presenting feature (eg Sweet's syndrome, infection, purpura) or be the sole manifestation with possible subsequent systemic spread (eg cutaneous T-cell lymphoma).
展开▼