首页> 外文期刊>Journal of Pharmacological and Toxicological Methods >hERG trafficking defects may underlie the delayed effects of GSK-A, an epigenetic modulator, on canine QTc interval

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hERG trafficking defects may underlie the delayed effects of GSK-A, an epigenetic modulator, on canine QTc interval

机译：hERG转运缺陷可能是表观遗传调节剂GSK-A对犬QTc间隔的延迟作用的基础

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来源
《Journal of Pharmacological and Toxicological Methods》 |2014年第3期|共5页
作者
Chaudhary Khuram; Valentine Patricia; Ingleby Lindsey; Brown Barry;
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正文语种 eng
中图分类药理学;
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入库时间 2022-08-19 03:41:26

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1. hERG trafficking defects may underlie the delayed effects of GSK-A, an epigenetic modulator, on canine QTc interval [J] . Chaudhary Khuram, Valentine Patricia, Ingleby Lindsey, Journal of Pharmacological and Toxicological Methods . 2014,第3期

机译：hERG转运缺陷可能是表观遗传调节剂GSK-A对犬QTc间隔的延迟作用的基础
2. The selective estrogen receptor modulator raloxifene inhibits cardiac delayed rectifier potassium currents and voltage-gated sodium current without QTc interval prolongation. [J] . Liu H, Yang L, Jin MW, Pharmacological research: The official journal of The Italian Pharmacological Society . 2010,第5期

机译：选择性雌激素受体调节剂雷洛昔芬可抑制心脏延迟整流器钾电流和电压门控钠电流，而不会延长QTc间隔。
3. Stereoselective Blockage of Quinidine and Quinine in the hERG Channel and the Effect of Their Rescue Potency on Drug-Induced hERG Trafficking Defect [J] . Meng Yan, Pan Fan, Yanhui Shi, International Journal of Molecular Sciences . 2016,第10期

机译：奎尼丁和奎宁在hERG通道中的立体选择性阻滞及其救援潜能对药物诱导的hERG贩运缺陷的影响
4. Discrimination of herg carrier from non-carrier adult patients with borderline prolonged QTc interval [C] . Couderc, J.P., Zareba, . 2005

机译：边缘性QTc间隔延长的非携带者成人患者与Herg携带者的区别
5. A new delay testing approach based on delay defect detection within slack intervals (DDSI). [D] . Yan, Haihua. 2005

机译：一种基于松弛间隔（DDSI）中的延迟缺陷检测的新延迟测试方法。
6. Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval – A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay Sensitivity [O] . Jörg Täubel, Georg Ferber, Ulrike Lorch, -1

机译：单剂量最多800 mg E-52862不会延长QTc间隔–心电图数据的药代动力学-药代动力学建模的回顾性验证该研究利用餐食对QTc的影响来证明ECG测定的敏感性
7. Evaluation of Moxifloxacin in Canine and Non‐Human Primate Telemetry Assays: Comparison of QTc Interval Prolongation by Timepoint and Concentration‐QTc Analysis [O] . Ray W. Chui, Joel Baublits, Fiona A. Chandra, 2021

机译：甘草酮类在犬和非人灵长类动物遥测中的评价：QTC间隔延长时间点及浓度 - QTC分析的比较
8. Effects of Delay, Intertrial Interval, Delay Behavior and Trimethyltin on Spatial Delayed Response in Rats [R] . Bushnell, P. J. 1987

机译：延迟，间期，延迟行为和三甲基锡对大鼠空间延迟反应的影响

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