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Pharmacological research: The official journal of The Italian Pharmacological Society

Pharmacological research: The official journal of The Italian Pharmacological Society

SCIMEDLINE

中文名称：药理研究：意大利药理学会的官方杂志

ISSN：1043-6618
出版周期：-

发文量：2842

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1.The impact of glutathione metabolism in autism spectrum disorder

机译：谷胱甘肽代谢在自闭症谱系中的影响
- 作者：Bjorklund Geir;Dosa Monica Daniela;Maes Michael;Dadar Maryam;Frye Richard E.;Peana Massimiliano;Chirumbolo Salvatore
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Autism;
- Glutathione;
- Oxidized glutathione;
- Glutathione redox ratio;
2.Functionally selective and biased agonists of muscarinic receptors

机译：功能性选择性和偏向的肌肉蛋白受体的激动剂
- 作者：Randakova Alena;Jakubik Jan
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Muscarinic receptors;
- Signalling bias;
- Functional selectivity;
- G-proteins;
- beta-arrestins;
3.Ginsenoside compound K- a potential drug for rheumatoid arthritis

机译：人参皂苷复合K-类风湿性关节炎的潜在药物
- 作者：Tang Mengshi;Xie Xi;Yang Yongyu;Li Fen
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Ginsenoside compound K;
- Rheumatoid arthritis;
- TNF-alpha-TNFR2;
- Glucocorticoid receptor (GR);
- beta-arrestins1/2;
4.Usage and promotion on Chinese medicine in Portuguese-speaking countries

机译：葡萄牙语国家中药的使用与促进
- 作者：Song Haoyan;Gao Jingran;Jia Hao
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Chinese medical science;
- Chinese medicine;
- Portuguese-speaking countries;
- Macau;
5.A novel method for automatic pharmacological evaluation of sucrose preference change in depression mice

机译：一种新的抑郁症蔗糖偏好变化自动药理评价的新方法
- 作者：Yin Chun-Yu;Li Lian-Di;Xu Chu;Du Zi-Wei;Wu Jia-Min;Chen Xiang;Xia Tian;Huang Shu-Ying;Meng Fan;Zhang Jing;Xu Pei-Jin;Hua Fu-Zhou;Muhammad Naveed;Han Feng;Zhou Qi-Gang
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Depression;
- Anhedonia;
- Novel method;
- Sucrose preference test;
- Automatic detection;
6.Behcet disease: From pathogenesis to novel therapeutic options

机译：Behcet疾病：从发病机制到新的治疗选择
- 作者：Rodriguez-Carrio Javier;Nucera Valeria;Masala Ignazio Francesco;Atzeni Fabiola
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Behcet disease;
- Therapy;
- Pathogenesis;
- Apremilast;
- IL-17;
7.Misleading meta-analyses of observational studies may generate unjustified alarms: The case of medications for nausea and vomiting in pregnancy

机译：误导性研究的荟萃分析可能产生不合理的警报：怀孕恶心和呕吐的药物的病例
- 作者：Biffi Annalisa;Rea Federico;Locatelli Anna;Cetin Irene;Filippelli Amelia;Corrao Giovanni
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
8.Targeting Cul3-scaffold E3 ligase complex via KLHL substrate adaptors for cancer therapy

机译：通过KLHL底物适配器靶向CUL3-支架E3连接酶复合物，用于癌症治疗
- 作者：Xiang Senfeng;Shi Xiaoxian;Chen Pengfei;Chen Yifan;Bing Shaowei;Jin Xizhi;Cao Ji;Wang Jinhu;Yang Bo;Shao Xuejing;He Qiaojun;Ying Meidan
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- KLHL;
- Cullin3-RING Ligase;
- Substrate adaptor;
- Target discovery;
- Cancer therapy;
9.Suppression of macrophage migration by down-regulating Src/FAK/P130Cas activation contributed to the anti-inflammatory activity of sinomenine

机译：通过下调SRC / FAK / P130CAS激活抑制巨噬细胞迁移导致SINOMENINE的抗炎活性
- 作者：Gao Wan-Jiao;Liu Jian-Xin;Xie Yie;Luo Pei;Liu Zhong-Qiu;Liu Liang;Zhou Hua
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Macrophage migration;
- Macrophage mesenchymal migration;
- Inflammation;
- Sinomenine;
- Macrophages depletion;
10.FOSL1 promotes tumorigenesis in colorectal carcinoma by mediating the FBXL2/Wnt/beta-catenin axis via Smurf1

机译：通过SMURF1介导FBXL2 / WNT /β-连环蛋白轴来促进结直肠癌中的肿瘤发生器
- 作者：Liu Yi;Yue Meng;Li Ze
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Fosl1;
- Smurf1;
- FBXL2;
- The Wnt/beta-catenin signaling;
- Colorectal carcinoma;
- Metastasis;
11.Prognostic impacts of beta-blockers in acute coronary syndrome patients without heart failure treated by percutaneous coronary intervention

机译：β-oplobers在急性冠状动脉综合征患者中对没有心脏冠状动脉失败的预后影响
- 作者：Chen Run-Zhen;Liu Chen;Zhou Peng;Li Jian-Nan;Zhou Jin-Ying;Wang Ying;Zhao Xiao-Xiao;Chen Yi;Song Li;Zhao Han-Jun;Yan Hong-Bing
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- beta-blockers;
- Acute coronary syndrome;
- Heart failure;
- Percutaneous coronary intervention;
12.Ubiquitin-specific protease 22 ameliorates chronic alcohol-associated liver disease by regulating BRD4

机译：特异性素特异性蛋白酶22通过调节BRD4来改善慢性醇类相关肝病
- 作者：Yan Ran;Chu Junyi;Zhou Yuanzhang;Shan Wen;Hu Yan;Lin Musen;Zhao Yan;Sun Ruimin;Wang Zhecheng;Lv Li;Wang Liming;Yao Jihong;Zhang Ning
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Ubiquitin-specific protease;
- Alcohol-associated liver disease;
- Inflammation;
- Deubiquitination;
- BRD4;
13.Pharmacological induction of mesenchymal-epithelial transition via inhibition of H2S biosynthesis and consequent suppression of ACLY activity in colon cancer cells

机译：H2S生物合成抑制作用中间充质上皮转换的药理诱导，随之地抑制结肠癌细胞中丙酮活性的影响
- 作者：Ascencao Kelly;Dilek Nahzli;Augsburger Fiona;Panagaki Theodora;Zuhra Karim;Szabo Csaba
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
14.Phytochemical add-on therapy to DMARDs therapy in rheumatoid arthritis: In vitro and in vivo bases, clinical evidence and future trends

机译：植物化学附加疗法对类风湿性关节炎的DMARDS治疗：体外和体内基地，临床证据和未来趋势
- 作者：Kour Gurleen;Haq Syed Assim;Bajaj Bijender Kumar;Gupta Prem N.;Ahmed Zabeer
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Phytochemicals;
- Rheumatoid arthritis;
- Methotrexate;
- Hepatotoxicity;
- Nephrotoxicity;
15.Optimal use of lipid-lowering therapy after acute coronary syndromes: A Position Paper endorsed by the International Lipid Expert Panel (ILEP)

机译：急性冠状动脉综合征后脂降低治疗的最佳用途：国际脂质专家小组（ILEP）认可的位置纸
- 作者：Banach Maciej;Penson Peter E.;Vrablik Michal;Bunc Matjaz;Dyrbus Krzysztof;Fedacko Jan;Gaita Dan;Gierlotka Marek;Jarai Zoltan;Magda Stefania Lucia;Margetic Eduard;Margoczy Roman;Durak-Nalbantic Azra;Ostadal Petr;Pella Daniel;Trbusic Matias;Udroiu Cristian Alexandru;Vlachopoulos Charalambos;Vulic Dusko;Fras Zlatko;Dudek Dariusz;Reiner Zeljko
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Combination therapy;
- Effectiveness;
- Ezetimibe;
- PCSK9 inhibitors;
- Safety;
- Statins;
16.The novel mechanisms and applications of exosomes in dermatology and cutaneous medical aesthetics

机译：外虫剂在皮肤病学和皮肤病医学美学的新机制和应用
- 作者：Xiong Mingchen;Zhang Qi;Hu Weijie;Zhao Chongru;Lv Wenchang;Yi Yi;Wang Yichen;Tang Hongbo;Wu Min;Wu Yiping
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Skin;
- Exosomes;
- Dermatology;
- Medical aesthetics;
- Tissue regeneration;
- Therapeutic applications;
17.Metabolomics identified new biomarkers for the precise diagnosis of pancreatic cancer and associated tissue metastasis (vol 156, 104805, 2020)

机译：代谢组学确定了新的生物标志物，用于胰腺癌和相关组织转移的精确诊断（Vol 156,104805,2020）
- 作者：Luo Xialin;Liu Jingjing;Wang Huaizhi;Lu Haitao
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
18.Anti-thrombotic effects mediated by dihydromyricetin involve both platelet inhibition and endothelial protection

机译：二氢霉素介导的抗血栓形成效应涉及血小板抑制和内皮保护
- 作者：Chen Shuai;Lv Keyu;Sharda Anish;Deng Jun;Zeng Wanjiang;Zhang Chao;Hu Qinghua;Jin Pengfei;Yao Guangmin;Xu Xulin;Ming Zhangyin;Fang Chao
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Dihydromyricetin;
- Thrombus formation;
- Platelets activation;
- Fibrin formation;
- Endothelial activation;
19.Ginsenosides for cardiovascular diseases; update on pre-clinical and clinical evidence, pharmacological effects and the mechanisms of action

机译：人参皂苷用于心血管疾病; 更新临床前和临床证据，药理效应和行动机制
- 作者：Sarhene Michael;Ni Jing Yu;Duncan Esi Sophia;Liu Zhihao;Li Sheng;Zhang Jing;Guo Rui;Gao Shan;Gao Xiumei;Fan Guanwei
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Cardiovascular disease;
- Ginseng;
- Ginsenoside;
- Pharmacological effects;
- Safety;
- Synergistic effects;
20.Effect of synbiotic supplementation on migraine characteristics and inflammatory biomarkers in women with migraine: Results of a randomized controlled trial

机译：Synbiotic补充对偏头痛妇女偏头痛特征和炎症生物标志物的影响：随机对照试验的结果
- 作者：Ghavami Abed;Khorvash Fariborz;Heidari Zahra;Khalesi Saman;Askari Gholamreza
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Migraine;
- Headache;
- Gut integrity;
- Inflammation;
- Synbiotics;
21.Biological evidence of gintonin efficacy in memory disorders

机译：记忆障碍中金蛋白疗效的生物学证据
- 作者：Jakaria Md;Azam Shofiul;Go Eun-Ae;Uddin Md Sahab;Jo Song-Hee;Choi Dong-Kug
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Gintonin;
- Glycolipoprotein;
- Agonist;
- LPARs;
- Neuroprotection;
- Memory disorders;
22.The role of brain barriers in the neurokinetics and pharmacodynamics of lithium

机译：脑屏障在锂锂神经动力学和药效学中的作用
- 作者：Luo Huilong;Chevillard Lucie;Bellivier Frank;Megarbane Bruno;Etain Bruno;Cisternino Salvatore;Decleves Xavier
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Blood-brain barrier;
- Lithium;
- Neurokinetics;
- Transporters;
- Plexus choroid;
- Pharmacodynamics;
23.Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Where will the drugs come from?

机译：肌间脑髓炎/慢性疲劳综合征（ME / CFS）：药物会来自哪里？
- 作者：Toogood Peter L.;Clauw Daniel J.;Phadke Sameer;Hoffman David
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Chronic fatigue syndrome;
- Myalgic encephalomyelitis;
- Systemic exertion intolerance disease;
- Drug discovery;
- COVID-19;
24.Enhanced therapeutic index of liposomal doxorubicin Myocet locally delivered by fibrin gels in immunodeficient mice bearing human neuroblastoma

机译：通过纤维蛋白凝胶在患有人神经母细胞瘤的免疫缺陷小鼠中局部递送的脂质体Doxorubicin Myocet的增强治疗指标
- 作者：Viale Maurizio;Bertone Vittorio;Maric Irena;Cilli Michele;Emionite Laura;Bocchini Vittorio;Ponzoni Mirco;Fontana Vincenzo;De Luca Fabrizio;Rocco Mattia
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Fibrin gel;
- Myocet;
- Caelyx;
- In vivo;
- Toxicity;
- Anti-tumour activity;
25.The receptor hypothesis and the pathogenesis of depression: Genetic bases and biological correlates

机译：受体假设和抑郁症的发病机制：遗传基因和生物相关性
- 作者：Wang Hui-Qin;Wang Zhen-Zhen;Chen Nai-Hong
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Depression;
- Receptors;
- Gene abnormality;
- Pathogenesis;
- Review;
26.Direct Keap1-kelch inhibitors as potential drug candidates for oxidative stress-orchestrated diseases: A review on In silico perspective

机译：直接Keap1-kelch抑制剂作为氧化胁迫 - 稳健疾病的潜在药物候选者：在Silico视角下审查
- 作者：Boyenle Ibrahim Damilare;Divine Ukachi Chiamaka;Adeyemi Rofiat;Ayinde Kehinde Sulaimon;Olaoba Olamide Tosin;Apu Chowdhry;Du Lei;Lu Qian;Yin Xiaoxing;Adelusi Temitope Isaac
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Oxidative stress;
- Keap1;
- Computer Aided Drug Design (CADD);
- In silico;
- Protein-protein interaction (PPI);
27.CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes

机译：CKIP-1对CX43的下游作用于NRF2信号通路的激活，以保护糖尿病中的肾纤维化
- 作者：Yang Yan;Li Jie;Zhang Lingqiang;Lin Zeyuan;Xiao Haiming;Sun Xiaohong;Zhang Meng;Liu Peiqing;Huang Heqing
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Diabetic nephropathy;
- Oxidative stress;
- Cx43;
- CKIP-1;
- Nrf2;
28.ERR gamma ligand HPB2 upregulates BDNF-TrkB and enhances dopaminergic neuronal phenotype

机译：ERR Gamma配体HPB2上调BDNF-TRKB并增强多巴胺能神经元表型
- 作者：Kim Hyo In;Lee Seungbeom;Lim Juhee;Chung Sungkyun;Koo Tae-Sung;Ji Yu-Geun;Suh Young-Ger;Son Woo Sung;Kim Seok-Ho;Choi Hyun Jin
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- BDNF;
- Dopaminergic neuron;
- ERR gamma;
- HPB2;
- Parkinson's disease;
29.Corrigendum to “Glucocorticoids impair platelet thromboxane biosynthesis in community-acquired pneumonia” [Pharmacol. Res. 131 (2018) 66–74]

机译：“糖皮质激素损害血小板血栓乳糖生物合成中的静脉曲张”药狼。 res。 131（2018）66-74]
- 作者：Roberto Cangemi;Roberto Carnevale;Cristina Nocella;Camilla Calvieri;Vittoria Cammisotto;Marta Novo;Valentina Castellani;Alessandra D’Amico;Chiara Zerbinati;Lucia Stefanini;Francesco Violi;in collaboration with the SIXTUS Study Group
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2018年第2018期
30.Dimerization of glucocorticoid receptors and its role in inflammation and immune responses

机译：糖皮质激素受体的二聚化及其在炎症和免疫应答中的作用
- 作者：Yang Mei;Chen Jingyu;Wei Wei
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Glucocorticoid receptor;
- Dimerization;
- Inflammation;
- Selective GR agonist/modulator;
31.The revitalization of antimicrobial peptides in the resistance era

机译：抗抗菌肽在抗性时代的振兴
- 作者：Liu Yuan;Shi Jingru;Tong Ziwen;Jia Yuqian;Yang Bingqing;Wang Zhiqiang
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Antimicrobial peptides;
- Antibiotic resistance;
- Bacteria;
- Multidrug-Resistant pathogens;
- Revitalization;
32.Xiao-Xu-Ming decoction prevented hemorrhagic transformation induced by acute hyperglycemia through inhibiting AGE-RAGE-mediated neuroinflammation

机译：小徐明汤通过抑制年龄愤怒介导的神经炎症通过抑制急性高血糖诱导出血转化
- 作者：Liu Nannan;Liu Chengdi;Yang Yujiao;Ma Guodong;Wei Guangyi;Liu Shan;Kong Linglei;Du Guanhua
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Xiao-Xu-Ming decoction;
- Hyperglycemia;
- Ischemic stroke;
- Hemorrhagic transformation;
- Blood-brain barrier;
- AGE-RAGE;
33.The hormetic dose-response mechanism: Nrf2 activation

机译：激素剂量反应机制：NRF2激活
- 作者：Calabrese Edward J.;Kozumbo Walter J.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Hormesis;
- Nrf2;
- Redox sensor;
- Acquired resilience;
- Biphasic dose response;
- Adaptive response;
34.Emerging roles of protein O-GlcNAcylation in cardiovascular diseases: Insights and novel therapeutic targets

机译：蛋白质O-Glcnacylation在心血管疾病中的新兴作用：见解和新的治疗目标
- 作者：Bolanle Israel Olapeju;Riches-Suman Kirsten;Williamson Ritchie;Palmer Timothy M.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Cardiovascular disease;
- Protein O-GlcNAcylation;
- O-GlcNAc transferase;
- O-GlcNAcase;
35.Behavioral and molecular effects of the antipsychotic drug blonanserin in the chronic mild stress model

机译：慢性轻度胁迫模型中抗精神病药物的行为和分子效应
- 作者：Paladini Maria Serena;Spero Vittoria;Begni Veronica;Marchisella Francesca;Guidi Alice;Gruca Piotr;Lason Magdalena;Litwa Ewa;Papp Maurisz;Riva Marco A.;Molteni Raffaella
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Blonanserin;
- Stress;
- Emotionality;
- Prefrontal cortex;
- Oxidative stress;
36.HDAC6 as privileged target in drug discovery: A perspective

机译：HDAC6作为药物发现的特权目标：一个观点
- 作者：Pulya Sravani;Amin Sk Abdul;Adhikari Nilanjan;Biswas Swati;Jha Tarun;Ghosh Balaram
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- HDAC6;
- HDAC6 inhibitor;
- Structure-activity relationship;
- Drug design and discovery;
- Cancer;
- Neurological disease;
37.A new stratification model for a population health risk assessment, based on a large cohort of patients infected by COVID-19

机译：基于Covid-19感染的大型患者的人口健康风险评估的新分层模型
- 作者：Blaco Roberto;Leoni Olivia;Cukaj Gjiliola;Ercolanoni Michele;Carnovale Carla
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
38.Combined inhibition of histone deacetylases and BET family proteins as epigenetic therapy for nerve injury-induced neuropathic pain

机译：组合抑制组蛋白脱乙酰酶的抑制作用，并将家庭蛋白质作为神经损伤诱导的神经病疼痛的表观遗传疗法
- 作者：Borgonetti Vittoria;Galeotti Nicoletta
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- HDAC;
- BET;
- Neuropathic pain;
- Microglia;
- NF-kappa B;
- Cytokines;
39.The 2-hydroxy-nevirapine metabolite as a candidate for boosting apolipoprotein A1 and for modulating anti-HDL antibodies

机译：将2-羟基 - 内赤素代谢物作为升压载脂蛋白A1和调节抗HDL抗体的候选物
- 作者：Marinho Aline T.;Batuca Joana R.;Miranda Joana P.;Caixas Umbelina;Dias Clara G.;Branco Teresa;Soto Karina;Pinheiro Pedro;Bourbon Mafalda;Marques M. Matilde;Antunes Alexandra M.;Monteiro Emilia C.;Pereira Sofia A.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Nevirapine;
- 2-Hydroxy-nevirapine;
- Drug biotransformation;
- High-density lipoprotein;
- Apolipoprotein A1;
- Anti-HDL antibodies;
40.Antiplatelet therapy in pregnancy: A systematic review

机译：怀孕抗血小板治疗：系统评价
- 作者：Nana Melanie;Morgan Holly;Moore Sacha;Lee Zong Xuan;Ang Eshen;Nelson-Piercy Catherine
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Antiplatelet therapy;
- Pregnancy;
- Regional anaesthesia;
- Clopidogrel;
- Systematic review;
41.Direct oral anticoagulants in the treatment of acute venous thromboembolism in patients with obesity: A systematic review with meta-analysis

机译：直接口服抗凝剂治疗肥胖患者急性静脉血栓栓塞中的治疗：通过META分析进行系统审查
- 作者：Mai V;Marceau-Ferron E.;Bertoletti L.;Lacasse Y.;Bonnet S.;Lega J. C.;Provencher S.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Venous thromboembolism;
- Obesity;
- Direct oral anticoagulant;
- Body mass index;
42.Cryptotanshinone alleviates chemotherapy-induced colitis in mice with colon cancer via regulating fecal-bacteria-related lipid metabolism

机译：Cryptotanshinone通过调节与粪便细菌相关的脂质代谢进行结肠癌，缓解化疗诱导的小鼠的结肠炎
- 作者：Wang Lin;Wang Rui;Wei Guang-yi;Zhang Rui-ping;Zhu Ying;Wang Zhe;Wang Shu-mei;Du Guan-hua
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
43.Meta-analysis of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: Reanalysis is needed

机译：血花素对肥胖，血压，CRP，血糖生物标志物和脂质剖面的鉴定荟萃分析：需要重新分析
- 作者：Hajhashemy Zahra;Saneei Parvane
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
44.Therapeutic potential of natural products against atherosclerosis: Targeting on gut microbiota

机译：天然产物对动脉粥样硬化的治疗潜力：靶向肠道微生物
- 作者：Zhao Xin;Oduro Patrick Kwabena;Tong Wanyu;Wang Yuefei;Gao Xiumei;Wang Qilong
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Gut microbiota;
- Atherosclerosis;
- Natural products;
- TMAO;
- SCFAs;
45.Antihypertensive drug valsartan as a novel BDK inhibitor

机译：抗高血压药物Valsartan作为新型BDK抑制剂
- 作者：Kitaura Yasuyuki;Shindo Daichi;Ogawa Tatsuya;Sato Ayato;Shimomura Yoshiharu
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Valsartan;
- BCAA catabolism;
- BDK inhibitor;
46.Pancreatitis initiated pancreatic ductal adenocarcinoma: Pathophysiology explaining clinical evidence

机译：胰腺炎发起胰腺导管腺癌：病理生理学解释临床证据
- 作者：Tao Xufeng;Xiang Hong;Pan Yue;Shang Dong;Guo Junchao;Gao Ge;Xiao Gary Guishan
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Pancreatitis;
- PDAC;
- Inflammation;
- Pancreatic cells;
- Signaling networks;
- Clinic implications;
47.Borneol in cardio-cerebrovascular diseases: Pharmacological actions, mechanisms, and therapeutics

机译：心血管血管疾病的冰片：药理行动，机制和治疗方法
- 作者：Liu Songyu;Long Yu;Yu Shuang;Zhang Dingkun;Yang Qiyue;Ci Zhimin;Cui Mingquan;Zhang Yulu;Wan Jinyan;Li Dan;Shi Ai;Li Nan;Yang Ming;Lin Junzhi
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Borneol;
- Cardio-cerebrovascular diseases;
- Pharmacological actions;
- Mechanisms;
- Therapeutics;
48.Response to comment by Bahar Rajabi: 'Effect of proanthocyanidins on blood pressure: A systematic review and meta-analysis of randomized controlled trials'

机译：响应巴哈拉·拉吉比亚评论：“花青胺蛋白对血压的影响：随机对照试验的系统审查和荟萃分析”
- 作者：Ren Jingyi;Ma Yuxia
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
49.A review of pharmacological and pharmacokinetic properties of Forsythiaside A

机译：连翘药物和药代动力学特性述评
- 作者：Gong Lihong;Wang Cheng;Zhou Honglin;Ma Cheng;Zhang Yafang;Peng Cheng;Li Yunxia
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Forsythiaside A;
- Pharmacological and pharmacokinetic properties;
- Anti-inflammation;
- Antivirus;
- Neuroprotection;
- Antioxidant;
50.Macrophage 3D migration: A potential therapeutic target for inflammation and deleterious progression in diseases

机译：巨噬细胞3D迁移：炎症和疾病中有害进展的潜在治疗靶标
- 作者：Gao Wan-Jiao;Liu Jian-Xin;Liu Meng-Nan;Yao Yun-Da;Liu Zhong-Qiu;Liu Liang;He Huan-Huan;Zhou Hua
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Macrophage;
- Macrophage migration;
- Inflammation;
- Autoimmune disease;
- Cancer;
- Extracellular matrix;
51.Microglial TLR4-induced TAK1 phosphorylation and NLRP3 activation mediates neuroinflammation and contributes to chronic morphine-induced antinociceptive tolerance

机译：微胶质瘤TLR4诱导的TAK1磷酸化和NLRP3激活介导神经炎性炎症，有助于慢性吗啡诱导的抗血汗耐受性
- 作者：Wang Haiyan;Huang Min;Wang Wenying;Zhang Yu;Ma Xiaqing;Luo Limin;Xu Xiaotao;Xu Liang;Shi Haibo;Xu Yongming;Wang Aizhong;Xu Tao
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Morphine tolerance;
- TLR4;
- toll-like receptor 4;
- TAK1;
- TGF-beta-activated kinase 1;
- Nod-like receptor protein 3;
- NLRP3;
- Neuroinflammation;
52.miRNA320a-3p/RUNX2 signal programming mediates the transgenerational inheritance of inhibited ovarian estrogen synthesis in female offspring rats induced by prenatal dexamethasone exposure

机译：miRNA320A-3P / RUNX2信号编程介导抑制产前地塞米松暴露诱导的雌性后代大鼠抑制卵巢雌激素合成的转基因遗传
- 作者：Gong Xiaohan;Zhang Jinzhi;Ge Caiyun;Yi Yiwen;Dai Shiyun;Fan Guanlan;Li Changrong;Zhang Yuanzhen;Wang Hui;Xu Dan
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Dexamethasone;
- Ovarian;
- Estradiol;
- Intrauterine origin;
- Transgenerational inheritance;
53.Diversity, molecular mechanisms and structure-activity relationships of marine protease inhibitors-A review

机译：海洋蛋白酶抑制剂的多样性，分子机制和结构 - 活性关系 - 评论
- 作者：Rauf Abdur;Khalil Anees Ahmed;Olatunde Ahmed;Khan Muneeb;Anwar Sirajudheen;Alafnan Ahmed;Rengasamy Kannan R. R.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Aspartic protease;
- Cysteine protease;
- Drug discovery;
- Marine protease inhibitors;
- Molecular mechanisms;
- Serine protease;
54.A sweet spot for macrophages: Focusing on polarization

机译：巨噬细胞的甜蜜点：专注于极化
- 作者：Yang Depeng;Yang Lijun;Cai Jialing;Hu Xibo;Li Huaxin;Zhang Xiaoqing;Zhang Xiaohan;Chen Xinghe;Dong Haiyang;Nie Huan;Li Yu
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Macrophages;
- Polarization;
- Glycobiology;
- Glycosylation;
- Glucose metabolism;
- Lectins;
55.Comment on 'Effect of proanthocyanidins on blood pressure: A systematic review and meta-analysis of randomized controlled trials'

机译：评论“花青霉素对血压的影响：随机对照试验的系统审查和荟萃分析”
- 作者：Rajabi Bahar;Nurizadeh Farnaz;Saneei Parvane
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
56.International policies and challenges on the legalization of traditional medicine/herbal medicines in the fight against COVID-19

机译：关于对Covid-19战斗中传统医学/草药法制化的国际政策和挑战
- 作者：Xiong Yin;Gao Min;van Duijn Bert;Choi Hoyoung;van Horssen Frits;Wang Mei
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- COVID-19;
- Traditional medicine;
- Herbal medicines;
- Policy;
- Legalization;
57.Pyroptosis is a critical immune-inflammatory response involved in atherosclerosis

机译：抛火剂是动脉粥样硬化的关键免疫炎症反应
- 作者：He Xiao;Fan Xuehui;Bai Bing;Lu Nanjuan;Zhang Shuang;Zhang Liming
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Atherosclerosis;
- Pyroptosis;
- ox-LDL;
- Cholesterol crystals;
58.Targeting the brain lesions using peptides: A review focused on the possibility of targeted drug delivery to multiple sclerosis lesions

机译：使用肽靶向脑病变：综合评估侧重于靶向药物递送至多发性硬化病变的可能性
- 作者：Rayatpour Atefeh;Javan Mohammad
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Multiple sclerosis lesions;
- Extracellular matrix;
- Cellular components;
- Targeting peptides;
- Drug delivery;
- Demyelination;
59.The potential modulatory role of curcumin on renal epithelial-to-mesenchymal transition in renal diseases

机译：姜黄素对肾病肾上皮对间充质转换的潜在调节作用
- 作者：Balakumar Pitchai;Alqahtani Ali;Mahadevan Nanjaian;Khan Noohu Abdulla;Thangathirupathi A.;Sambathkumar R.;Dhanaraj S. A.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
60.Ficolin-2 serum levels predict the occurrence of acute coronary syndrome in patients with severe carotid artery stenosis

机译：Ficolin-2血清水平预测严重颈动脉狭窄患者急性冠状动脉综合征的发生
- 作者：Carbone Federico;Valente Alessia;Perego Carlo;Bertolotto Maria;Pane Bianca;Spinella Giovanni;Palombo Domenico;De Simoni Maria-Grazia;Montecucco Fabrizio;Fumagalli Stefano
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Atherosclerosis;
- Complement system;
- Biomarkers;
- Plaque vulnerability;
61.The role of short-chain fatty acids in intestinal barrier function, inflammation, oxidative stress, and colonic carcinogenesis

机译：短链脂肪酸在肠道阻隔功能，炎症，氧化应激和结肠癌发生中的作用
- 作者：Liu Pinyi;Wang Yanbing;Yang Ge;Zhang Qihe;Meng Lingbin;Xin Ying;Jiang Xin
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Short-chain fatty acids;
- Inflammation;
- Carcinogenesis;
- Intestinal barrier;
- Oxidative stress;
62.Profibrotic mechanisms of DPP8 and DPP9 highly expressed in the proximal renal tubule epithelial cells

机译：DPP8和DPP9在近端肾小管上皮细胞中高表达的DPP8和DPP9的突触性机制
- 作者：Zhang Yuzhan;Li Ke;Li Yan;Zhao Weihao;Wang Li;Chen Zhao;Ma Xiaotao;Yao Tian;Wang Jinhua;Dong Wei;Li Xiancheng;Tian Xuefei;Fu Rongguo
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Tubulointerstitial fibrosis;
- DPP8/DPP9;
- TGF-beta 1;
- Smad;
63.Delineation of the functional properties exhibited by the Zinc-Activated Channel (ZAC) and its high-frequency Thr(128) Ala variant (rs2257020) in Xenopus oocytes

机译：描绘锌激活通道（ZAC）和其高频THR（128）ALA变体（RS2257020）划分的功能性质在Xenopus卵母细胞中
- 作者：Madjroh Nawid;Davies Paul A.;Smalley Joshua L.;Kristiansen Uffe;Soderhielm Pella C.;Jensen Anders A.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
64.Vascular reactivity stimulated by TMA and TMAO: Are perivascular adipose tissue and endothelium involved?

机译：TMA和TMAO刺激的血管反应性：是否有血管脂肪组织和涉及内皮？
- 作者：Restini Carolina Baraldi A.;Fink Gregory D.;Watts Stephanie W.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
65.Lactoferrin as a regenerative agent: The old-new panacea?

机译：乳铁蛋白作为再生剂：旧的灵丹妙药？
- 作者：Antoshin Artem A.;Shpichka Anastasia I;Huang Guilin;Chen Kuo;Lu Pengwei;Svistunov Andrey A.;Lychagin Alexey V;Lipina Marina M.;Sinelnikov Mikhail Y.;Reshetov Igor V;Timashev Peter S.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Lactoferrin;
- Lactotransferrin;
- Lactoferricin;
- Signaling;
- Regeneration;
- Stem cells;
- Tissue engineering;
- Regenerative medicine;
- Cell therapy;
66.Suppression of apoptosis in vascular endothelial cell, the promising way for natural medicines to treat atherosclerosis

机译：抑制血管内皮细胞的细胞凋亡，自然药物治疗动脉粥样硬化的有前途的方法
- 作者：Duan Huxinyue;Zhang Qing;Liu Jia;Li Ruolan;Wang Dan;Peng Wei;Wu Chunjie
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Atherosclerosis;
- Vascular endothelial cells;
- Apoptosis;
- Natural medicines;
67.Targeting autophagy using saponins as a therapeutic and preventive strategy against human diseases

机译：使用Saponins靶向自噬作为针对人类疾病的治疗和预防策略
- 作者：Han Bing;He Chengwei
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Autophagy;
- Saponins;
- Cancer;
- Neurodegenerative diseases;
- Atherosclerosis;
68.Allopregnanolone in mood disorders: Mechanism and therapeutic development

机译：情绪疾病中的亚丙酮：机制和治疗发展
- 作者：Chen Shiyi;Gao Lijuan;Li Xiaoyu;Ye Yiping
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Allopregnanolone;
- Depression;
- Anxiety;
- Postpartum depression;
- TSPO;
69.Assessment of medullary and extramedullary myelopoiesis in cardiovascular diseases

机译：在心血管疾病中评估髓质和髓外髓鞘
- 作者：Abdali Anahita;Marinkovic Goran
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Haematopoiesis;
- Myelopoiesis;
- Atherosclerosis;
- Myocardial infarction;
- HSCs;
- Neutrophils;
- Monocytes;
- Macrophages;
70.Diphenyl diselenide protects motor neurons through inhibition of microglia-mediated inflammatory injury in amyotrophic lateral sclerosis

机译：二苯基五烯酯通过抑制微细胞介导的肌营养的侧面硬化症中的微胶质介导的炎症损伤来保护运动神经元
- 作者：Zhang Chunting;Wang Hongyong;Liang Weiwei;Yang Yueqing;Cong Chaohua;Wang Ying;Wang Shuyu;Wang Xudong;Wang Di;Huo Di;Feng Honglin
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Diphenyl diselenide;
- Neuroinflammation;
- Microglia;
- ALS;
- Neuroprotection;
71.Adipokines as a therapeutic target by metformin to improve metabolic function: A systematic review of randomized controlled trials

机译：adipokines作为二甲双胍的治疗靶标，以改善代谢功能：对随机对照试验的系统审查
- 作者：Dludla Phiwayinkosi V;Nkambule Bongani B.;Mazibuko-Mbeje Sithandiwe E.;Nyambuya Tawanda M.;Mxinwa Vuyolwethu;Mokgalaboni Kabelo;Ziqubu Khanyisani;Cirilli Ilenia;Marcheggiani Fabio;Louw Johan;Tiano Luca
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Metformin;
- Metabolic syndrome;
- Diabetes mellitus;
- Adipokines;
- Insulin resistance;
- Therapeutic target;
72.Is there a link between inorganic polyphosphate (polyP), mitochondria, and neurodegeneration?

机译：无机多磷酸盐（息肉），线粒体和神经变性之间是否存在链路？
- 作者：Emily Borden A.;Matthew Furey;Nicholas Gattone J.;Vedangi Hambardikar D.;Hua Liang Xiao;Ernest Scoma R.;Antonella Abou Samra;Lakeshia D-Gary R.;Dayshaun Dennis J.;Daniel Fricker;Cindy Garcia;Jiang ZeCheng;Shariq Khan A.;Dheenadhayalan Kumarasamy;Hasmitha Kuppala;Savannah Ringrose;Evan Rosenheim J.;Kimberly Van Exel;Sai Vudhayagiri Hemanth;Zhang Jiarui;Zhang Zhaowen;Mariona Guitart-Mampel;Pedro Urquiza;Maria Solesio E.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Mitochondria;
- Inorganic polyphosphate;
- polyp;
- Neurodegeneration;
- Alzheimer's disease;
- Parkinson's disease;
73.EGFR mutation mediates resistance to EGFR tyrosine kinase inhibitors in NSCLC: From molecular mechanisms to clinical research

机译：EGFR突变在NSCLC中介导抗EGFR酪氨酸激酶抑制剂的抗性：从分子机制到临床研究
- 作者：Dong Rui-Fang;Zhu Miao-Lin;Liu Ming-Ming;Xu Yi-Ting;Yuan Liu-Liu;Bian Jing;Xia Yuan-Zheng;Kong Ling-Yi
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- EGFR mutations;
- NSCLC;
- EGFR-TKI resistance;
- Overcoming drug resistance;
- Future development;
74.Farnesol induces mitochondrial/peroxisomal biogenesis and thermogenesis by enhancing the AMPK signaling pathway in vivo and in vitro

机译：法内尼胆汁通过增强体内和体外的AMPK信号通路来诱导线粒体/过氧硅基生物发生和热生成
- 作者：Cho Seon Yeon;Lim Seona;Ahn Kwang Seok;Kwak Hyun Jeong;Park Jinbong;Um Jae-Young
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Farnesol;
- Thermogenesis;
- Mitochondria;
- Peroxi some;
- AMPK alpha;
75.Sortilin-derived peptides promote pancreatic beta-cell survival through CREB signaling pathway

机译：Sortilin衍生的肽通过Creb信号通路促进胰腺β细胞存活
- 作者：Daziano Guillaume;Blondeau Nicolas;Beraud-Dufour Sophie;Abderrahmani Amar;Rovere Carole;Heurteaux Catherine;Mazella Jean;Lebrun Patricia;Coppola Thierry
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Beta-cell protection;
- Calcium influx;
- CREB activation;
- Neuropeptide;
- Sortilin-released propeptide;
76.Regulatory mechanisms and therapeutic targeting of vasculogenic mimicry in hepatocellular carcinoma

机译：肝细胞癌中血管原性的调节机制及治疗靶向
- 作者：Zheng Ning;Zhang Shaoqin;Wu Wenda;Zhang Nan;Wang Jichuang
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
77.SIRT3 as a potential therapeutic target for heart failure

机译：SIRT3作为心力衰竭的潜在治疗目标
- 作者：Chen Jie;Chen Shiqi;Zhang Bingxia;Liu Junwei
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Heart failure;
- Cardiac remodeling;
- Sirtuins;
- SIRT3;
78.Medioresinol as a novel PGC-1 alpha activator prevents pyroptosis of endothelial cells in ischemic stroke through PPAR alpha-GOT1 axis

机译：Medioresinol作为新型PGC-1α激活剂可防止通过PPAR alpha-get1轴阻止内皮细胞糊化肾上腺细胞
- 作者：Wang Yunjie;Guan Xin;Gao Cheng-Long;Ruan Wenchen;Zhao Shunyi;Kai Guoyin;Li Fei;Pang Tao
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Medioresinol;
- Endothelial cells;
- Pyroptosis;
- Ischemic stroke;
- PGC-1 alpha;
- PPAR alpha;
- Phenylalanine;
79.A bibliometric study of COVID-19 research in Web of Science

机译：科学网站Covid-19研究的生物计量研究
- 作者：Su Meiming;Xu Suowen;Weng Jianping
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
80.Resveratrol-mediated attenuation of superantigen-driven acute respiratory distress syndrome is mediated by microbiota in the lungs and gut

机译：白藜芦醇介导的超抗原驱动的急性呼吸窘迫综合征的衰减是通过微生物生物介导的肺部和肠道
- 作者：Alghetaa Hasan;Mohammed Amira;Zhou Juhua;Singh Narendra;Nagarkatti Mitzi;Nagarkatti Prakash
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- ARDS;
- Cytokine storm;
- Resveratrol;
- Superantigen;
- SEB;
- Microbiota;
81.The Nrf2 in the pathophysiology of the intestine: Molecular mechanisms and therapeutic implications for inflammatory bowel diseases

机译：NRF2在肠道的病理生理学中：炎症性肠病的分子机制和治疗意义
- 作者：Piotrowska Marta;Swierczynski Mikolaj;Fichna Jakub;Piechota-Polanczyk Aleksandra
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Nrf2;
- Inflammatory bowel diseases;
- Ulcerative colitis;
- Crohn's diseases;
- Colorectal cancer;
- Gut microbiota;
82.Saliva sampling for chasing SARS-CoV-2: A Game-changing strategy

机译：追逐SARS-COV-2的唾液抽样：更改博弈的策略
- 作者：Borghi Elisa;Massa Valentina;Carmagnola Daniela;Dellavia Claudia;Parodi Chiara;Ottaviano Emerenziana;Sangiorgio Arianna;Barcellini Lucia;Gambacorta Greta;Forlanini Federica;Zuccotti Gian Vincenzo
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
83.Enteropeptidase inhibition improves obesity by modulating gut microbiota composition and enterobacterial metabolites in diet-induced obese mice

机译：肠肽酶抑制通过调节肠道微生物酵母组合物和饮食诱导的肥胖小鼠的肠杆菌代谢物来改善肥胖症
- 作者：Sugama Jun;Moritoh Yusuke;Yashiro Hiroaki;Tsuchimori Kazue;Watanabe Masanori
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Enteropeptidase;
- Obesity;
- Gut microbiota;
- Akkermansia;
- Short-chain fatty acid;
84.Tetrahydropalmatine triggers angiogenesis via regulation of arginine biosynthesis

机译：四氢丙氨酸通过调节精氨酸生物合成来触发血管生成
- 作者：Cui Herong;Yang Xuexin;Wang Zhidong;Li Guoping;Li Lei;Huo Su;Zhang Beibei;He Rui;Chen Kedian;Xu Bing;Wang Penglong;Lei Haimin
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Tetrahydropalmatine;
- Angiogenesis;
- Metabolomics;
- Arginine biosynthesis;
85.Whole transcriptome sequencing and integrated network analysis elucidates the effects of 3,8-Di-O-methylellagic acid 2-O-glucoside derived from Sanguisorba offcinalis L., a novel differentiation inducer on erythroleukemia cells

机译：整个转录组测序和集成网络分析阐明了3,8-Di-O-甲基化酸2-O-葡糖苷的影响，衍生自三胞嘧啶细胞的新型分化诱导剂。
- 作者：Long Wang;Liu Sha;Li Xiao-Xuan;Shen Xin;Zeng Jing;Luo Jie-Si;Li Ke-Ru;Wu An-Guo;Yu Lu;Qin Da-Lian;Hu Guang-Qiang;Yang Jing;Wu Jian-Ming
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
86.Hydrophobic and polar interactions of FDA-approved small molecule protein kinase inhibitors with their target enzymes

机译：FDA批准的小分子蛋白激酶抑制剂与其靶酶的疏水性和极性相互作用
- 作者：Roskoski Robert Jr.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
87.Specific phytocannabinoid compositions are associated with analgesic response and adverse effects in chronic pain patients treated with medical cannabis

机译：特异性植物植物组合物与医疗大麻治疗治疗的慢性疼痛患者的镇痛反应和不良反应有关
- 作者：Aviram Joshua;Lewitus Gil M.;Pud Dorit;Procaccia Shiri;Berman Paula;Yellin Ben;Vysotski Yelena;Hazan Or;Eisenberg Elon;Meiri David
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Phytocannabinoids;
- Medical cannabis;
- Adverse effects;
- Efficacy;
88.Melatonin supplementation in the management of obesity and obesity-associated disorders: A review of physiological mechanisms and clinical applications

机译：褪黑激素补充肥胖和肥胖相关疾病的管理：对生理机制和临床应用的综述
- 作者：Genario Rafael;Cipolla-Neto Jose;Bueno Allain A.;Santos Heitor O.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Obesity therapy;
- Weight loss;
- Melatonin;
- Obesity;
- Endocrinology;
89.Mimicking bone microenvironment: 2D and 3D in vitro models of human osteoblasts

机译：模仿骨髓：2D和3D体外模型的人成骨细胞
- 作者：Yuste I;Luciano F. C.;Gonzalez-Burgos E.;Lalatsa A.;Serrano D. R.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Bone regeneration;
- in vitro models;
- Osteoblast;
- 3D bioprinting;
- Microfluidics;
- Tissue engineering;
- Hydrogels;
90.Melatonin and regulation of autophagy: Mechanisms and therapeutic implications

机译：褪黑激素和自噬的调节：机制和治疗意义
- 作者：Wu Jinjing;Bai Yang;Wang Yaguang;Ma Jun
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Melatonin;
- Mitophagy;
- Ischemia/reperfusion injury;
- Cancer;
- Neurodegenerative diseases;
91.Reproductive toxic potential of phthalate compounds - State of art review

机译：邻苯二甲酸酯化合物的生殖毒性潜力 - 艺术综述
- 作者：Sedha Sapna;Lee Hoomin;Singh Siddhartha;Kumar Sunil;Jain Subodh;Ahmad Ajaz;Bin Jardan Yousef A.;Sonwal Sonam;Shukla Shruti;Simal-Gandara Jesus;Xiao Jianbo;Huh Yun Suk;Han Young-Kyu;Bajpai Vivek K.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Phthalates;
- Reproductive toxicity;
- Developmental toxicity;
- Epidemiology;
92.Properties of FDA-approved small molecule phosphatidylinositol 3-kinase inhibitors prescribed for the treatment of malignancies

机译：FDA批准的小分子磷脂酰肌醇3-激酶抑制剂，处方治疗恶性肿瘤
- 作者：Roskoski Robert Jr.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
93.Liver organoid as a 3D in vitro model for drug validation and toxicity assessment

机译：肝脏有机体作为药物验证和毒性评估的3D体外模型
- 作者：Brooks Anastasia;Liang Xiaowen;Zhang Yonglong;Zhao Chun-Xia;Roberts Michael S.;Wang Haolu;Zhang Lei;Crawford Darrell H. G.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Liver organoid;
- Drug validation;
- Toxicity assessment;
94.Molecular mechanisms of mitophagy and its roles in neurodegenerative diseases

机译：乳化物的分子机制及其在神经变性疾病中的作用
- 作者：Li Xinnan;Huang Longjian;Lan Jiaqi;Feng Xinhong;Li Pingping;Wu Lei;Peng Ying
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
95.Epigenetics in NAFLD/NASH: Targets and therapy

机译：NAFLD / NASH中的表皮遗传学：目标和治疗
- 作者：Sodum Nalini;Kumar Gautam;Bojja Sree Lalitha;Kumar Nitesh;Rao C. Mallikarjuna
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- HDAC;
- Non-alcoholic fatty liver disease;
- Non-alcoholic steatohepatitis;
- DNA methylation;
- Histone modification;
- MicroRNAs;
96.Oligosaccharides from fucosylated glycosaminoglycan prevent breast cancer metastasis in mice by inhibiting heparanase activity and angiogenesis

机译：来自岩藻糖基化糖胺聚糖的寡糖通过抑制乙酰肝素酶活性和血管生成来防止小鼠乳腺癌转移
- 作者：Zhou Lutan;Yin Ronghua;Gao Na;Sun Huifang;Chen Dingyuan;Cai Ying;Ren Lin;Yang Lian;Zuo Zhili;Zhang Hongbin;Zhao Jinhua
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Oligosaccharides;
- Heparanase;
- Angiogenesis;
- Metastasis;
97.Inflammation in Bipolar Disorder (BD): Identification of new therapeutic targets

机译：双相障碍（BD）中的炎症：鉴定新的治疗目标
- 作者：Pereira Ana Catarina;Oliveira Joana;Silva Sonia;Madeira Nuno;Pereira Claudia M. F.;Cruz Maria T.
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Bipolar disorder;
- Immune system;
- Inflammation;
- Cytokines;
- Drug therapy;
- Therapeutic targets;
98.Pharmacotherapy of obesity: An update

机译：肥胖的药物治疗：更新
- 作者：Cignarella Andrea;Busetto Luca;Vettor Roberto
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Obesity;
- Diabetes;
- Weight management;
- Glucagon receptor family;
- Individual variation;
99.Dichotomous role of microtubule associated protein tau as a biomarker of response to and a target for increasing efficacy of taxane treatment in cancers of epithelial origin

机译：微管相关蛋白质Tau的二均法作用作为反应的生物标志物和增加紫杉烷治疗在上皮起源癌症中的疗效
- 作者：Barbolina Maria V
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Biomarker;
- Taxane;
- Breast cancer;
- Ovarian cancer;
- Chemoresistance;
- Alzheimer's disease;
100.The muscle to bone axis (and viceversa): An encrypted language affecting tissues and organs and yet to be codified?

机译：骨骼到骨轴（和伏赞的人）：影响组织和器官的加密语言，尚未被编纂？
- 作者：Bosco Francesca;Musolino Vincenzo;Gliozzi Micaela;Nucera Saverio;Carresi Cristina;Zito Maria Caterina;Scarano Federica;Scicchitano Miriam;Reale Fabio;Ruga Stefano;Maiuolo Jessica;Macri Roberta;Guarnieri Lorenza;Coppoletta Anna Rita;Mollace Rocco;Muscoli Carolina;Palma Ernesto;Mollace Vincenzo
- 期刊名称：《Pharmacological research: The official journal of The Italian Pharmacological Society》 | 2021年第1期
- Muscle atrophy;
- Bone;
- Osteoporosis;
- Osteopenia;
- Musculoskeletal apparatus;
- Myokines;

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