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首页> 外文期刊>Journal of Pharmacological and Toxicological Methods >How do large pharmaceutical companies mitigate concerns of drug-induced QT prolongation in drug discovery?

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How do large pharmaceutical companies mitigate concerns of drug-induced QT prolongation in drug discovery?

机译：大型制药公司如何减轻对药物发现中药物诱导的QT延长的担忧？

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来源
《Journal of Pharmacological and Toxicological Methods》 |2014年第3期|共1页
作者
Valentin Jean-Pierre; Baker David; Gallacher David; Gintant Gary; Greiter-Wilke Andrea; Guillon Jean-Michel; Himmel Herbert; Kasai Chieko; Leishman Derek; Levesque Paul; Louttit James; Ratcliffe Sian; Sannajust Frederick; Suter Willi; Vargas Hugo; Yamamoto Keiji;
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正文语种 eng
中图分类药理学;
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1. How do large pharmaceutical companies mitigate concerns of drug-induced QT prolongation in drug discovery? [J] . Valentin Jean-Pierre, Baker David, Gallacher David, Journal of Pharmacological and Toxicological Methods . 2014,第3期

机译：大型制药公司如何减轻对药物发现中药物诱导的QT延长的担忧？
2. Drug-Induced QT/QTc Interval Shortening: Lessons from Drug-Induced QT/QTc Prolongation [J] . Malik Marek Drug safety: An international journal of medical toxicology and drug experience . 2016,第7期

机译：药物诱导的QT / QTc间隔缩短：药物诱导的QT / QTc延长的经验教训
3. Preface to Special Issue “Non-clinical Database for Evaluation of Drug-Induced QT Interval Prolongation by QT PRODACT (QT Interval Prolongation: Project for Database Construction)” [J] . Keiji Yamamoto Journal of pharmacological sciences. . 2005,第5期

机译：特刊“通过QT PRODACT评估药物诱导的QT间隔延长的非临床数据库（QT间隔延长：数据库建设项目）”的序言
4. Effects of Lead Position, Cardiac Rhythm Variation and Drug-induced QT Prolongation on Performance of Machine Learning Methods for ECG Processing [C] . Marat Bogdanov, Salim Baigildin, Aigul Fabarisova, Ural Symposium on Biomedical Engineering, Radioelectronics and Information Technology . 2020

机译：导联位置，心律变化和药物诱导的QT延长对ECG加工机器学习方法性能的影响
5. Potential mechanisms for drug-induced prolongation of QT interval and genesis of torsades de pointes evaluated in the failing rabbit heart. [D] . Kijtawornrat, Anusak. 2007

机译：在衰竭的心脏中评估了药物引起的QT间隔延长和扭转性扭转的潜在机制。
6. Strategies to reduce the risk of drug-induced QT interval prolongation: a pharmaceutical company perspective [O] . C E Pollard, J-P Valentin, T G Hammond 2008

机译：降低药物引起的QT间隔延长的风险的策略：制药公司的观点
7. Strategies to reduce the risk of drug-induced QT interval prolongation: a pharmaceutical company perspective [O] . Pollard, C E, Valentin, J-P, Hammond, T G 2008

机译：降低药物引起的QT间隔延长的风险的策略：制药公司的观点

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