Thanks to the progress of science and technology, the prenatal approach to the identification of possible alterations of the offspring of the human species is now within our grasp, however, the homogeneity of its benefits is marred by several factors which I will briefly discuss in this Editorial. The factors I refer to are of two kinds: one is that the scientific approach is not only a matter of progress in one of the classical disciplines, e.g., classical cytogenetics, ultrasonography, the analysis of blood parameters in the pregnant woman, or more recently, molecular diagnosis that involves sampling of prenatal foetal tissue or fluids, but rather it is the complex integration of all these disciplines that, in a complementary or combined approach, converge to achieve the final aim, namely to foster the progress of technology, knowledge and science in the field of prenatal analysis of the health status of the offspring.
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