Reactions of carbonyl compounds in basic solutions. Part 30. The effect of 2-formyl,2,6-diformyl and 2-trifluoroacetyl substituents on the alkaline and neutral hydrolysis of methyl benzoate and phenyl acetate

摘要

Rate coefficients are measured for the alkaline hydrolysis of methyl 2-formyl-, 2,6-diformyl- and 2-trifluoroacetyl-benzoates and for the alkaline and neutral hydrolysis of 2-formyl-, 2,6-diformyl-4-methyl- and 2-trifluoroacetyl-phenyl acetates in water at several temperatures: the relative rates of hydrolysis and activation parameters demonstrate neighbouring group participation by the acyl-carbonyl groups in the ester hydrolysis.