Is lowering low-density lipoprotein an effective strategy to reduce cardiac risk?-Promise of Low-Density Lipoprotein-Lowering Therapy for Primary and Secondary Prevention

摘要

One of the foremost medical advances of the past 2 decades has been proof that elevated low-density lipoprotein (LDL) is a cause of atherosclerotic cardiovascular disease (ASCVD) and that lowering of LDL levels will reduce risk for ASCVD.1-2 The application of this knowledge in clinical and public health arenas offers the opportunity to greatly reduce morbidity and mortality from ASCVD. This article outlines the rationale underlying this opportunity.