Benzimidazolylidene Carbene Ligated Palladium Catalysis of the Heck Reaction in Aqueous Media

摘要

A highly effective,easy to handle and environmentally benign process for a palladium mediated Heck reaction was developed.The in situ prepared 3-component system,Pd(OAc)2/1,3-dialkylbenzimidazolium chlorides (LHX = 1a-g) and CS2CO3,catalyzes quantitatively the Heck coupling of aryl bromides under mild conditions in aqueous media.