Palladium-catalyzed Heck reaction of aryl bromides in aqueous media using tris(N-heterocyclic carbene) ligands

摘要

A highly effective, easy to handle and environmentally benign process for palladium-mediated Heck reaction was developed. The in situ prepared three-component system composed of palladium(II) acetate, a tris(azolinium) bromide and potassium tert-butoxide, quantitatively catalyzes the Heck reaction of aryl bromides in aqueous media.