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Electroencephalograms in the diagnosis and management of the epilepsies

机译:脑电图在癫痫病的诊断和治疗中的作用

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The generic term 'epilepsy' embraces a particular group of disorders of the CNS but by itself is of limited clinical value. Intense clinical and genetic research over the last few decades has identified a large number of well-defined epilepsy syndromes with different clinical, electroencephalograms (EEG), neuropsychological and neuroim-aging profiles, natural history and prognosis, conditions that ultimately require different management. There is evidence that early treatment can reduce the risk of seizure recurrence (First Seizure Trial Group, 1993), and its efficacy depends largely on the appropriate drug choice in relation to the particular clinical syndrome. Therefore, a diagnosis of epilepsy is no longer sufficient; identification of the particular form or syndrome is the cornerstone of meaningful, optimal management.
机译:通用术语“癫痫症”涵盖了中枢神经系统的特定疾病组,但其本身具有有限的临床价值。在过去的几十年中,大量的临床和遗传学研究已经发现了许多定义明确的癫痫综合征,它们具有不同的临床,脑电图(EEG),神经心理学和神经影像学特征,自然病史和预后,最终需要进行不同管理。有证据表明早期治疗可以降低癫痫发作复发的风险(First Seizure Trial Group,1993),其疗效在很大程度上取决于针对特定临床综合征的适当药物选择。因此,癫痫的诊断不再足够。特定形式或综合症的识别是有意义的,最佳管理的基石。

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