Hepatocytes from induced pluripotent stem cells: a giant leap forward for hepatology.

摘要

With an estimated 467,000 new cases per year worldwide, cirrhosis remains the fourth most common cause of death in the United States. Except for complete liver transplants, which are only available to a few, to date, there is no medical treatment available. Clearly, abrogation of end-stage liver disease is of great clinical significance. In this issue of HEPATOLOGY, two investigations reveal significant and seminal strides to solving the problem of liver replacement therapies