Differential Pharmacokinetics of Diclofenac Potassium for Oral Solution vs Immediate-Release Tablets From a Randomized Trial: Effect of Fed and Fasting Conditions

Chen Cuiping; Bujanover Shay; Kareht Stephanie; Rapoport Alan M.

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Differential Pharmacokinetics of Diclofenac Potassium for Oral Solution vs Immediate-Release Tablets From a Randomized Trial: Effect of Fed and Fasting Conditions

机译：双氯芬酸钾口服液与速释片差异药代动力学的随机试验：进食和禁食条件的影响

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摘要

ObjectiveTo compare the pharmacokinetics of, and food effect on, diclofenac potassium delivered as an oral solution vs an immediate-release tablet.

机译：目的比较双氯芬酸钾口服液和速释片的药代动力学和食品效果。

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来源
《Headache》 |2015年第2期|共11页
作者
Chen Cuiping; Bujanover Shay; Kareht Stephanie; Rapoport Alan M.;
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正文语种 eng
中图分类诊断学;
关键词
diclofenac potassium; liquid formulation; rate of absorption; pharmacokinetics; migraine treatment; nonsteroidal anti-inflammatory medication;

机译：双氯芬酸钾;液体制剂;吸收率;药代动力学;偏头痛治疗;非甾体类抗炎药;

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1. Differential Pharmacokinetics of Diclofenac Potassium for Oral Solution vs Immediate-Release Tablets From a Randomized Trial: Effect of Fed and Fasting Conditions [J] . Chen Cuiping, Bujanover Shay, Kareht Stephanie, Headache . 2015,第2期

机译：双氯芬酸钾口服液与速释片差异药代动力学的随机试验：进食和禁食条件的影响
2. Pharmacokinetic profile of extended-release versus immediate-release oral naproxen sodium after single and multiple dosing under fed and fasting conditions: two randomized, open-label trials [J] . Laurora Irene, Wang Yuan International journal of clinical pharmacology and therapeutics . 2016,第10期

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3. Pharmacokinetics and Bioequivalence of Rasagiline Tablets in Chinese Healthy Subjects Under Fasting and Fed Conditions: An Open, Randomized, Single-Dose, Double-Cycle, Two-Sequence, Crossover Trial [J] . Yinjuan Li, Lu Qi, Haihong Bai, Frontiers in Neuropharmacology . 2020,第a期

机译：在禁食和喂养条件下的中国健康受试者中rasagiline片剂的药代动力学和生物等效性：开放，随机，单剂量，双循环，双序列，交叉试验
4. Pharmacokinetic Studies with a Mucoadhesive Multilayer Extended-Release Tablet Formulation of Levodopa-Carbidopa in Fed and Fasted Beagles [C] . Peyman Moslemy, Bennett Carter, Nicholas Cardoso, Controlled Release Society Annual Meeting and Exposition . 2007

机译：左旋多巴-卡比多巴在美联储和禁食比格犬中的粘膜粘附多层延长释放片制剂的药代动力学研究
5. The Effects of Intermittent Fasting on Quality of Life and Happiness: A Randomized Control Trial [D] . De León, Anateresa. 2021

机译：间歇性禁食对生活质量和幸福的影响：随机控制试验
6. Single-dose pharmacokinetics of 2 or 3 tablets of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen (MNK-155) under fed and fasted conditions: two randomized open-label trials [O] . Krishna Devarakonda, Kenneth Kostenbader, Michael J. Giuliani, 2015

机译：在进食和禁食条件下2或3片双相立即释放/延长释放的氢可酮酒石酸氢盐/对乙酰氨基酚（MNK-155）的单剂量药代动力学：两项随机开放标签试验
7. Single-dose pharmacokinetics of 2 or 3 tablets of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen (MNK-155) under fed and fasted conditions: two randomized open-label trials [O] . Krishna Devarakonda, Kenneth Kostenbader, Michael J. Giuliani, 2015

机译：在进食和禁食条件下2或3片双相立即释放/延长释放的氢可酮酒石酸氢盐/对乙酰氨基酚（MNK-155）的单剂量药代动力学：两项随机开放标签试验

Differential Pharmacokinetics of Diclofenac Potassium for Oral Solution vs Immediate-Release Tablets From a Randomized Trial: Effect of Fed and Fasting Conditions

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