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Frontiers in Neuropharmacology

中文名称：神经药理学前沿

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1.MicroRNA-221-3p Suppresses the Microglia Activation and Seizures by Inhibiting of HIF-1α in Valproic Acid-Resistant Epilepsy

机译：MicroRNA-221-3P通过抑制抗血尿酸性癫痫中的HIF-1α来抑制微胶质增长活化和癫痫发作
- 作者：Meng Fu;Yiqing Zhu;Junqi Zhang;Wei Wu;Yunxia Sun;Xuemei Zhang;Jie Tao;Zhiping Li
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- valproic acid-resistant epilepsymicroRNA-221-3phypoxia-inducible factor-1αmicroglianeuroinflammation;
2.MeCP2 Epigenetic Silencing of Oprm1 Gene in Primary Sensory Neurons Under Neuropathic Pain Conditions

机译：神经性疼痛条件下原发性感觉神经元的MECP2肌动蛋白沉默
- 作者：Na Sun;Lina Yu;Yibo Gao;Longfei Ma;Jinxuan Ren;Ying Liu;Dave Schwinn Gao;Chen Xie;Ying Wu;Lieju Wang;Juncong Hong;Min Yan
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- morphineneuropathic painMORDNA methylationhistone acetylation;
3.Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain

机译：奥氮滨诱导的下丘脑星形胶质细胞和通过内质网胁迫的损伤的受体-4信号传导与奥氮平诱导的体重增加有关
- 作者：Meng He;Kun Qian;Ying Zhang;Xu-Feng Huang;Chao Deng;Baohua Zhang;Guanbin Gao;Jing Li;Hao Xie;Taolei Sun
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- antipsychoticsweight gainglial fibrillary acidic proteinS100 calcium binding protein BTLR4-MyD88 signalingendoplasmic reticulum stress;
4.Editorial: Application of Plant Secondary Metabolites to Pain Neuromodulation

机译：社论：植物次级代谢物在止痛性中的应用
- 作者：Rajeev K.Singla;Adriana Gibara Guimar?es;Gokhan Zengin
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- painnociceptionnatural productssecondary metabolitesphytochemicalsmedicinal plants;
5.Small-Conductance Ca2+-Activated K+ Channels 2 in the Hypothalamic Paraventricular Nucleus Precipitates Visceral Hypersensitivity Induced by Neonatal Colorectal Distension in Rats

机译：下丘脑椎间盘内核中的小导电CA2 +活化的K +通道2沉淀着大鼠新生儿结肠直肠扩张诱导的内敏超敏反应
- 作者：Ning-Ning Ji;Lei Du;Ying Wang;Ke Wu;Zi-Yang Chen;Rong Hua;Yong-Mei Zhang
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- PKAneonatal colorectal distensionvisceral hypersensitivityratshypothalamic paraventricular nucleussmall-conductance Ca2+-activated K+ channel 2;
6.Aberrant Auditory Steady-State Response of Awake Mice Induced by Chronic Interferon-α Treatment

机译：慢性干扰素-α治疗诱导的清醒小鼠的异常听觉稳态响应
- 作者：Yingzhuo Li;Xuejiao Wang;Jingyu Chen;Zijie Li;Pingting Yang;Ling Qin
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- interferon-alphadepressive-like behaviormicrogliaastrocytesauditory cortexEEG;
7.Berberine Reduces Aβ42 Deposition and Tau Hyperphosphorylation via Ameliorating Endoplasmic Reticulum Stress

机译：通过改善内质网胁迫降低Aβ42沉积和TAU高磷酸化
- 作者：Yue Wu;Qingjie Chen;Bing Wen;Ninghua Wu;Benhong He;Juan Chen
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- berberineAlzheimer’s diseaseendoplasmic reticulum stressAβ42 productiontau hyperphosphorylation;
8.Rhein Relieves Oxidative Stress in an Aβ1-42 Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis

机译：Rhein通过激活SIRT1 / PGC-1α-调节的线粒体生物粒子生物粒子生物粒子生物粒子模型在Aβ1-42低聚体 - 负载沉重的神经元模型中减轻氧化应激
- 作者：Zhihui Yin;Xinyue Geng;Zhengyi Zhang;Ying Wang;Xiaoyan Gao
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- β-amyloidoxidative stressrheinmitochondrial biogenesissirtuin 1peroxisome proliferator-activated receptor gamma coactivator 1-alpha;
9.Case Report: Multiple Seizures After a Diphenoxylate-Atropine Overdose in a Small Child

机译：案例报告：在小孩子中二苯氧基化物过量后多发性癫痫发作
- 作者：Chun-Hui Wang;Li-Jia Song;Yang Yang;Xiao-Peng Qu;Li Lan;Bei Liu
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- childrentoxic encephalopathyseizureneuropharmacologydiphenoxylate-atropine;
10.Refractory and Super-Refractory Status Epilepticus in Nerve Agent-Poisoned Rats Following Application of Standard Clinical Treatment Guidelines

机译：神经剂中毒大鼠难治性和超耐火材料状态癫痫患者在施用标准临床治疗指南后
- 作者：Julia E.Morgan;Sara C.Wilson;Benjamin J.Travis;Kathryn H.Bagri;Kathleen T.Pagarigan;Hannah M.Belski;Cecelia Jackson;Kevin M.Bounader;Jessica M.Coppola;Eden N.Hornung;James E.Johnson;Hilary S.McCarren
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- status epilepticusrefractoryseizurenerve agentorganophosphatesoman;
11.The Selective SIK2 Inhibitor ARN-3236 Produces Strong Antidepressant-Like Efficacy in Mice via the Hippocampal CRTC1-CREB-BDNF Pathway

机译：选择性Sik2抑制剂ARN-3236通过海马CRTC1-CREB-BDNF途径在小鼠中产生强烈的抗抑郁药物。
- 作者：Yue Liu;Wenqian Tang;Chunhui Ji;Jianghong Gu;Yanmei Chen;Jie Huang;Xinyi Zhao;Yingfang Sun;Chengniu Wang;Wei Guan;Jianfeng Liu;Bo Jiang
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- ARN-3236brain-derived neurotrophic factorcyclic AMP response element binding proteinCREB-Regulated transcription coactivator 1depressionhippocampussalt-inducible kinase 2;
12.Sex Differences in the Nicotinic Acetylcholine Receptor System of Rodents: Impacts on Nicotine and Alcohol Reward Behaviors

机译：啮齿动物烟碱乙酰胆碱受体体系的性差异：对尼古丁和酒精奖励行为的影响
- 作者：Janna K.Moen;Anna M.Lee
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- nicotinic acetylcholine receptorsex differencesalcoholnicotineaddiction;
13.Neurochemistry of Visual Attention

机译：神经化学的视觉关注
- 作者：Denise Elfriede Liesa Lockhofen;Christoph Mulert
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- visual attentionattentional selectionneurochemistrypsychopharmacologyneuromodulator;
14.Allopregnanolone Decreases Evoked Dopamine Release Differently in Rats by Sex and Estrous Stage

机译：亚丙醇尼龙通过性和叙事阶段诱发多巴胺释放不同的多巴胺释放
- 作者：Ana Paula S.Dornellas;Giovana C.Macedo;Minna H.McFarland;Alexander Gómez-A;Todd K.O’Buckley;Claudio Da Cunha;A.Leslie Morrow;Donita L.Robinson
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- neurosteroidallopregnanoloneprogesteronevoltammetrydopaminenucleus accumbens;
15.Role of the Dopaminergic System in the Striatum and Its Association With Functional Recovery or Rehabilitation After Brain Injury

机译：多巴胺能系统在纹状体中的作用及其与脑损伤后功能恢复或康复的关系
- 作者：Antonio Verduzco-Mendoza;Paul Carrillo-Mora;Alberto Avila-Luna;Arturo Gálvez-Rosas;Adriana Olmos-Hernández;Daniel Mota-Rojas;Antonio Bueno-Nava
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- dopaminecorticostriatal pathwayfunctional recoverytraumatic brain injurydopamine receptors;
16.Effect of Ulinastatin on Early Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Surgery: A Systemic Review and Meta-Analysis

机译：ulinastatin对术后认知功能障碍在术后手术的早期术后认知功能障碍：全身审查和荟萃分析
- 作者：Mei Duan;Fangyan Liu;Huiqun Fu;Shuai Feng;Xue Wang;Tianlong Wang
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- elderly patientssurgeryperioperative inflammationpostoperative cognitive dysfunctionulinastatinmeta-analysis;
17.Nerve Growth Factor Biodelivery: A Limiting Step in Moving Toward Extensive Clinical Application?

机译：神经生长因子生物次数：转向广泛临床应用的限制步骤？
- 作者：Giuseppe Alastra;Luigi Aloe;Vito Antonio Baldassarro;Laura Calzà;Maura Cescatti;Jason Thomas Duskey;Maria Letizia Focarete;Daria Giacomini;Luciana Giardino;Valentina Giraldi;Luca Lorenzini;Marzia Moretti;Irene Parmeggiani;Michele Sannia;Giovanni Tosi
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- nerve growth factornanomedicinedrug deliveryelectrospinninghydrogels;
18.Determination of Diffusion Kinetics of Ketamine in Brain Tissue: Implications for in vitro Mechanistic Studies of Drug Actions

机译：脑组织中氯胺酮扩散动力学的测定：对药物作用的体外机制研究的影响
- 作者：Zachary Geiger;Brett VanVeller;Zarin Lopez;Abdel K.Harrata;Kathryn Battani;Lauren Wegman-Points;Li-Lian Yuan
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- ketamineantidepressantpharmacokineticsbrainhippocampus sliceNMDA receptorsynaptic plasticity;
19.Danzhi Xiaoyao Powder Promotes Neuronal Regeneration by Downregulating Notch Signaling Pathway in the Treatment of Generalized Anxiety Disorder

机译：Danzhi Xiaoyao粉促进神经元再生通过下调Notch信号通路在治疗广泛性焦虑症
- 作者：Chao Liu;Zhenhao Ying;Zifa Li;Long Zhang;Xin Li;Wenbo Gong;Jiang Sun;Xuejing Fan;Ke Yang;Xingchen Wang;Sheng Wei;Ning Dong
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- Generalized anxiety disorderDZXYShippocampusNotchneuron regeneration;
20.Plasma Levels of Brain-Derived Neurotrophic Factor and S100B in Relation to Antidepressant Response to Ketamine

机译：血浆级脑衍生的神经营养因子和S100b的血浆水平与氯胺酮的抗抑郁药反应相关
- 作者：Haitang Jiang;Emma R.Veldman;Mikael Tiger;Carl-Johan Ekman;Johan Lundberg;Per Svenningsson
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- ketaminemBDNFS100Bmajor depressive disorderneurotrophin;
21.D-Amphetamine Rapidly Reverses Dexmedetomidine-Induced Unconsciousness in Rats

机译：D- amphetamine迅速逆转Dexmedetomidine诱导的大鼠无意识
- 作者：Risako Kato;Edlyn R.Zhang;Olivia G.Mallari;Olivia A.Moody;Kathleen F.Vincent;Eric D.Melonakos;Morgan J.Siegmann;Christa J.Nehs;Timothy T.Houle;Oluwaseun Akeju;Ken Solt
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- dexmedetomidineketamined-amphetamineprefrontal cortexemergence from anesthesia;
22.Alpha/Beta-Hydrolase Domain-Containing 6: Signaling and Function in the Central Nervous System

机译：含α/β-水解酶域6：中枢神经系统中的信号和功能
- 作者：Haofuzi Zhang;Xin Li;Dan Liao;Peng Luo;Xiaofan Jiang
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- ABHD6endocannabinoid systemCPT1CAMPA receptorneurological diseases;
23.Scopolamine Impairs Spatial Information Recorded With “Miniscope” Calcium Imaging in Hippocampal Place Cells

机译：CoCopolamine损害了在海马放置细胞中记录的“Miniscope”钙成像记录的空间信息
- 作者：Dechuan Sun;Ranjith Rajasekharan Unnithan;Chris French
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- scopolamineplace cellsminiature microscopecalcium imagingmAChRs;
24.Neuroprotective and Anti-Inflammatory Effect of Pterostilbene Against Cerebral Ischemia/Reperfusion Injury via Suppression of COX-2

机译：活体苯乙烯对脑缺血/再灌注损伤通过抑制COX-2的神经保护和抗炎作用
- 作者：Wenjun Yan;Dongqing Ren;Xiaoxue Feng;Jinwen Huang;Dabin Wang;Ting Li;Dong Zhang
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- cerebral ischemia reperfusionpterostilbeneinflammationoxidative stressCOX-2;
25.Isorhynchophylline Ameliorates Cerebral Ischemia/Reperfusion Injury by Inhibiting CX3CR1-Mediated Microglial Activation and Neuroinflammation

机译：Isorhynchophylline通过抑制CX3CR1介导的小胶质激活和神经肾性炎症来改善脑缺血/再灌注损伤
- 作者：Yuanyuan Deng;Ruirong Tan;Fei Li;Yuangui Liu;Jingshan Shi;Qihai Gong
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- Isorhynchophyllinecerebral ischemia/reperfusion injuryneuroinflammationmicrogliaC-X3-C motif chemokine receptor 1;
26.Editorial: “Novel Pain Therapeutics: From Basic Research to Clinical Translation and Rehabilitation”

机译：社论：“新型疼痛治疗方法：从基础研究到临床翻译和康复”
- 作者：Damiana Scuteri;Tsukasa Sakurada;Paolo Tonin;Maria Tiziana Corasaniti;Giacinto Bagetta
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- painsensitizationnatural and synthetic analgesicsopioidsdementiacognitive impairmentrehabilitation;
27.Enhancement of Oxytocin in the Medial Prefrontal Cortex Reverses Behavioral Deficits Induced by Repeated Ketamine Administration in Mice

机译：内侧前额叶皮质中催产素的增强反转小鼠反复氯胺酮施用的行为缺陷
- 作者：Weili Zhu;Zengbo Ding;Zhihui Zhang;Xiao Wu;Xiaoya Liu;Ya Zhang;Suxia Li;Liping Zhou;Geng Tian;Jing Qin
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- oxytocinketaminemedial prefrontal cortexsocial avoidancecognitive impairmentinflammatory mediatorsimmune markers;
28.Inborn Errors of Metabolism Associated With Autism Spectrum Disorders: Approaches to Intervention

机译：与自闭症频谱疾病相关的原始误差：干预方法
- 作者：Tamara ?igman;Danijela Petkovi? Ramad?a;Goran ?imi?;Ivo Bari?
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- autism spectrum disorderearly diagnosisgenetic testinginborn errors of metabolismtherapeutic principles;
29.Hesperidin Interacts With CREB-BDNF Signaling Pathway to Suppress Pentylenetetrazole-Induced Convulsions in Zebrafish

机译：Hesperidin与CREB-BDNF信号传导途径相互作用，以抑制斑马鱼中的五苯甲唑诱导的痉挛
- 作者：Pallavi Sharma;Savita Kumari;Jatin Sharma;Rituraj Purohit;Damanpreet Singh
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- brain-derived neurotrophic factorclonic-like seizuresepilepsyc-fosflavanone glycosidein silico dockingil-10zebrafish larva;
30.Lentivirus-Carried microRNA-195 Rescues Memory Deficits of Alzheimer’s Disease Transgenic Mouse by Attenuating the Generation of Amyloid Plaques

机译：Lentivirus的MicroRNA-195通过减轻淀粉样斑块的产生来拯救阿尔茨海默病转基因小鼠的记忆缺陷
- 作者：Dan Su;Yani Chai;Junkai Yang;Xuqiao Wang;Ying Liu;Jing Ma;Xin Tang;Chandan Mishra;Shah Ram Chandra;Weidong Yue;Jing Ai
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- miR-195APP/PS1 transgenic miceAβ plaquescognitionmultiple molecular targets;
31.The Potential of Lisosan G as a Possible Treatment for Glaucoma

机译：Lisosan G的潜力作为青光眼的可能治疗
- 作者：Rosario Amato;Maria Grazia Rossino;Maurizio Cammalleri;Anna Maria Timperio;Giuseppina Fanelli;Massimo Dal Monte;Laura Pucci;Giovanni Casini
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- inflammationneuroprotectionnutraceuticalsoxidative stresspattern electroretinogram;
32.Krill Oil Alleviated Methamphetamine-Induced Memory Impairment via the MAPK Signaling Pathway and Dopaminergic Synapse Pathway

机译：KRILL OIL通过MAPK信号通路和多巴胺能突触途径缓解甲基苯丙胺诱导的记忆损伤
- 作者：Qin Ru;Xiang Tian;Qi Xiong;Congyue Xu;Lin Chen;Yuxiang Wu
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- krill oilmethamphetaminememory deficitsnetwork pharmacologyhippocampus;
33.Comprehensive Bibliometric Analysis of the Kynurenine Pathway in Mood Disorders: Focus on Gut Microbiota Research

机译：情绪障碍犬素碱途径的综合生物毛细管分析：专注于肠道微生物群研究
- 作者：Xiuqing Zhu;Jinqing Hu;Shuhua Deng;Yaqian Tan;Chang Qiu;Ming Zhang;Xiaojia Ni;Haoyang Lu;Zhanzhang Wang;Lu Li;Yayan Luo;Shanqing Huang;Tao Xiao;Shujing Liu;Xiaolin Li;Dewei Shang;Yuguan Wen
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- kynurenine pathwaymood disordersdepressionbipolar disorderbibliometric analysisgut microbiotamicrobiota-gut-brain axisimmune system;
34.Blockade of β-Adrenergic Receptors by Propranolol Disrupts Reconsolidation of Drug Memory and Attenuates Heroin Seeking

机译：通过普萘洛尔阻断β-肾上腺素能受体破坏了药物记忆的重新渗透并衰减海洛因寻求
- 作者：Liangpei Chen;Shihao Huang;Chang Yang;Feilong Wu;Qiuyao Zheng;He Yan;Jie Yan;Yixiao Luo;Ewa Galaj
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- drug memorypropranololreconsolidationrelapseheroindrug seekingreinstatement;
35.Efficacy and Safety of Monoclonal Antibody Against Calcitonin Gene-Related Peptide or Its Receptor for Migraine: A Systematic Review and Network Meta-analysis

机译：单克隆抗体对Calcitonin基因相关肽或其对偏头痛受体的功效和安全性：系统审查和网络Meta分析
- 作者：Xing Wang;Yuqi Chen;Jinlei Song;Chao You
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- migrainecalcitonin gene-related peptidemonoclonal antibodyheadachemeta-analysis;
36.Ethanol-Dependent Synthesis of Salsolinol in the Posterior Ventral Tegmental Area as Key Mechanism of Ethanol’s Action on Mesolimbic Dopamine

机译：乙醇依赖于后腹部三巴胺乙醇作用的关键机制的乙醇依赖性合成。乙醇作用的关键机制
- 作者：Valentina Bassareo;Roberto Frau;Riccardo Maccioni;Pierluigi Caboni;Cristina Manis;Alessandra T.Peana;Rossana Migheli;Simona Porru;Elio Acquas
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- acetaldehydebrain microdialysisdopamineethanolμ opioid receptorsnucleus accumbens shellposterior ventral tegmental areasalsolinol;
37.Altered Spontaneous Glutamatergic and GABAergic Activity in the Peritumoral Cortex of Low-Grade Gliomas Presenting With History of Seizures

机译：随着癫痫发作史的低级胶质瘤的Peritumoral皮层改变了自发性谷氨酸和胃肠杆菌活性
- 作者：Soumil Dey;Ramesh Sharanappa Doddamani;Aparna Banerjee Dixit;Manjari Tripathi;Meher Chand Sharma;P.Sarat Chandra;Jyotirmoy Banerjee
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- low-grade gliomaseizureperitumoral tissueglutamatergic activityGABAergic activity;
38.Osthole Ameliorates Estrogen Deficiency-Induced Cognitive Impairment in Female Mice

机译：汤孔改善了雌激素缺乏症的雌性小鼠的认知障碍
- 作者：Frank Adu-Nti;Xu Gao;Jia-Min Wu;Jing Li;Javed Iqbal;Riaz Ahmad;Xin-Ming Ma
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- estradiolovariectomydepression-like behaviorscognitive deficithippocampus;
39.Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke

机译：自噬参与α7烟碱乙酰胆碱受体对缺血性卒中的神经保护作用
- 作者：Zhe-Qi Xu;Jing-Jing Zhang;Ni Kong;Guang-Yu Zhang;Ping Ke;Ting Han;Ding-Feng Su;Chong Liu
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- α7 nicotinic acetylcholine receptorautophagyischemic strokeneuroprotectionapoptosis;
40.Gaboxadol in Fragile X Syndrome: A 12-Week Randomized, Double-Blind, Parallel-Group, Phase 2a Study

机译：Gaboxadol在脆弱的X综合征：12周随机化，双盲，并联组，第2阶段研究
- 作者：Dejan B.Budimirovic;Kelli C.Dominick;Lidia V.Gabis;Maxwell Adams;Mathews Adera;Linda Huang;Pamela Ventola;Nicole R.Tartaglia;Elizabeth Berry-Kravis
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- OV101gaboxadolfragile X syndromeFMR1GABAAsafetyefficacyrandomized study;
41.Activation of Antioxidant and Proteolytic Pathways in the Nigrostriatal Dopaminergic System After 3,4-Methylenedioxymethamphetamine Administration: Sex-Related Differences

机译：3,4-甲基二氧基甲嘧啶管理后硝基滴体多巴胺能系统中抗氧化剂和蛋白水解途径的激活：性与性差异
- 作者：Giulia Costa;Francesca Felicia Caputi;Marcello Serra;Nicola Simola;Laura Rullo;Serena Stamatakos;Fabrizio Sanna;Marc Germain;Maria-Grazia Martinoli;Sanzio Candeletti;Micaela Morelli;Patrizia Romualdi
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- gluthatione peroxidasehyperthermiasuperoxide dismutasetyrosine hydroxylaseubiquitin-proteasome system;
42.Inhibiting YAP in Endothelial Cells From Entering the Nucleus Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury

机译：抑制内皮细胞中的粘液进入核心在缺血再灌注损伤期间衰减血脑屏障损伤
- 作者：Shuaishuai Gong;Huifen Ma;Fan Zheng;Juan Huang;Yuanyuan Zhang;Boyang Yu;Fang Li;Junping Kou
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- YAPverteporfinendothelial cellsblood-brain barrierischemic stroke;
43.Cocaine Reduces the Neuronal Population While Upregulating Dopamine D2-Receptor-Expressing Neurons in Brain Reward Regions: Sex-Effects

机译：可卡因减少神经元群，同时脑奖励地区的上调多巴胺D2-受体的神经元：性效应
- 作者：Kevin Clare;Chelsea Pan;Gloria Kim;Kicheon Park;Juan Zhao;Nora D.Volkow;Zhicheng Lin;Congwu Du
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- cocainedopamine-2 receptordynorphinenkephalinneuroadaptationsex differences;
44.The Effect of Dehydroepiandrosterone Treatment on Neurogenesis, Astrogliosis and Long-Term Cocaine-Seeking Behavior in a Cocaine Self-Administration Model in Rats

机译：脱氢贫康松治疗对大鼠可卡因自我管理模型中的神经发生，十分术，长期可卡因寻求行为的影响
- 作者：Hadas Ahdoot-Levi;Ofri Croitoru;Tzofnat Bareli;Einav Sudai;Hilla Peér-Nissan;Avi Jacob;Iris Gispan;Rachel Maayan;Abraham Weizman;Gal Yadid
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- addictionneurogensisastrogliosiscocaineself-administrationDHEA;
45.Venlafaxine Attenuated the Cognitive and Memory Deficit in Mice Exposed to Isoflurane Alone

机译：venlafaxine衰减单独暴露于异氟烷的小鼠中的认知和记忆缺损
- 作者：Liang Li;Chunhai Zhang
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- POCDGABAA receptors α5neuroinflammationY mazememory;
46.Neuronal Mitochondrial Dysfunction and Bioenergetic Failure in Inflammation-Associated Depression

机译：炎症相关抑郁症中神经元线粒体功能障碍和生物能量衰竭
- 作者：Angela Maria Casaril;Robert Dantzer;Carlos Bas-Orth
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- depressioninflammationmitochondriabioenergeticsneurons;
47.Single-Target Versus Multi-Target Drugs Versus Combinations of Drugs With Multiple Targets: Preclinical and Clinical Evidence for the Treatment or Prevention of Epilepsy

机译：单身目标与多目标药物与具有多个目标的药物组合：治疗或预防癫痫的临床前和临床证据
- 作者：Wolfgang L?scher
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- antiseizure drugsantiepileptic drugspolypharmacydesigned multiple ligandsdrug resistanceepileptogenesis;
48.HEXA-018, a Novel Inducer of Autophagy, Rescues TDP-43 Toxicity in Neuronal Cells

机译：Hexa-018是一种新型自噬诱导剂，拯救了神经元细胞中的TDP-43毒性
- 作者：Shinrye Lee;Myungjin Jo;Hye Eun Lee;Yu-Mi Jeon;Seyeon Kim;Younghwi Kwon;Junghwa Woo;Shin Han;Ji Young Mun;Hyung-Jun Kim
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- catecholautophagymitochondrial dysfunctionTDP-43ALS;
49.Repurposing Immunomodulatory Imide Drugs (IMiDs) in Neuropsychiatric and Neurodegenerative Disorders

机译：在神经精神和神经变性障碍中重新培养免疫调节酰亚胺药物（IMID）
- 作者：Yoo Jin Jung;David Tweedie;Michael T.Scerba;Dong Seok Kim;Maria Francesca Palmas;Augusta Pisanu;Anna R.Carta;Nigel H.Greig
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- IMiDs?neurodegenarative diseasesneuropsychaitric disordersneuroinflammationthalidomidepomalidomide;
50.Tortoise Plastron and Deer Antler Gelatin Prevents Against Neuronal Mitochondrial Dysfunction In Vitro: Implication for a Potential Therapy of Alzheimer’s Disease

机译：乌龟素质和鹿鹿茸明胶可防止在体外进行神经元线粒体功能障碍：对阿尔茨海默病的潜在治疗的影响
- 作者：Dan Cheng;Xin-Jing Yang;Lu Zhang;Zong-Shi Qin;Wen-Qi Li;Hai-Chun Xu;Zhang-Jin Zhang
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- deer antler gelatintortoise plastron gelatinAlzheimer’s diseaseoxidative damagemitochondrial dysfunction;
51.Acute Pharmacological Effects and Oral Fluid Concentrations of the Synthetic Cannabinoids JWH-122 and JWH-210 in Humans After Self-Administration: An Observational Study

机译：自我管理后，人类合成大麻素和JWH-210的急性药理效应和口腔流体浓度：观察研究
- 作者：Lucia Martínez;Nunzia La Maida;Esther Papaseit;Clara Pérez-Ma?á;Lourdes Poyatos;Manuela Pellegrini;Simona Pichini;Mireia Ventura;Liliana Galindo;Francesco Paolo Busardò;Magí Farré
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- JWH-122JWH-210synthetic cannabinoid receptor agonists (SCRAs)physiological effectssubjective effects;
52.Structure-Guided Computational Methods Predict Multiple Distinct Binding Modes for Pyrazoloquinolinones in GABAA Receptors

机译：结构引导的计算方法预测GABAA受体中吡唑喹啉酮的多种不同的结合模式
- 作者：Jure Fabjan;Filip Koniuszewski;Benjamin Schaar;Margot Ernst
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- GABAA receptorallosteric modulationpyrazoloquinolinonefunctional selectivitycomputational dockingpharmacophore analysis;
53.The Extracellular Domains of GluN Subunits Play an Essential Role in Processing NMDA Receptors in the ER

机译：格伦亚基的细胞外结构域在呃加工NMDA受体中发挥着重要作用
- 作者：Martin Horak;Petra Barackova;Emily Langore;Jakub Netolicky;Paula Rivas-Ramirez;Kristyna Rehakova
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- disulfide bridgesglutamate receptorglycosylationexcitatory synapseposttranslational modification;
54.A Phase 1, Dose-Ranging Study to Assess Safety and Psychoactive Effects of a Vaporized 5-Methoxy-N, N-Dimethyltryptamine Formulation (GH001) in Healthy Volunteers

机译：1期，剂量测量研究，以评估蒸发的5-甲氧基-N，N-二甲基三丁胺制剂（GH001）在健康志愿者中的安全性和精神效应
- 作者：Johannes Reckweg;Natasha L.Mason;Cees van Leeuwen;Stefan W.Toennes;Theis H.Terwey;Johannes G.Ramaekers
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- 5-MeO-DMTpsychedelic agentspsychoactivecognitiondose finding;
55.PDE10A Inhibitors—Clinical Failure or Window Into Antipsychotic Drug Action?

机译：PDE10A抑制剂 - 临床失败或窗口进入抗精神病药物吗？
- 作者：Frank S.Menniti;Thomas A.Chappie;Christopher J.Schmidt
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- schizophreniaPDE10Abasal gangliadopaminecyclic nucleotide phosphodiesterasemedium spiny neuronantipsychotic action;
56.Melatonin Alleviates Acute Sleep Deprivation-Induced Memory Loss in Mice by Suppressing Hippocampal Ferroptosis

机译：褪黑素通过抑制海马硬化，减轻了急性睡眠剥夺诱导的小鼠内存损失
- 作者：Xintong Wang;Zixu Wang;Jing Cao;Yulan Dong;Yaoxing Chen
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- sleep deprivationferroptosismelatoninhippocampusmemory lossintracellular signaling pathwayMT2;
57.Maternal Nicotine Exposure Alters Hippocampal Microglia Polarization and Promotes Anti-inflammatory Signaling in Juvenile Offspring in Mice

机译：母尼古丁暴露改变了海马小胶质细胞偏振，促进小鼠幼年后代的抗炎信号传导
- 作者：Li Zhou;Xinrong Tao;Gang Pang;Min Mu;Qixian Sun;Fei Liu;Yuting Hu;Huihui Tao;Bing Li;Keyi Xu
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- maternal nicotine exposurehippocampusmicrogliamouseOffspring;
58.Drug Repurposing in the Treatment of Traumatic Brain Injury

机译：毒品重新调整创伤性脑损伤的治疗
- 作者：Michael K.Ghiam;Shrey D.Patel;Alan Hoffer;Warren R.Selman;Barry J.Hoffer;Michael E.Hoffer
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- traumatic brain injuryconcussionN-acetyl cysteineminocyclinephenserine;
59.Cocaine-Induced Changes in Tonic Dopamine Concentrations Measured Using Multiple-Cyclic Square Wave Voltammetry in vivo

机译：可卡因诱导在体内多循环方波伏安法测量滋补多巴胺浓度的变化
- 作者：Jason Yuen;Abhinav Goyal;Aaron E.Rusheen;Abbas Z.Kouzani;Michael Berk;Jee Hyun Kim;Susannah J.Tye;Charles D.Blaha;Kevin E.Bennet;Dong-Pyo Jang;Kendall H.Lee;Hojin Shin;Yoonbae Oh
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- cocainetonic dopamineaddictionvoltammetrynucleus accumbensneurosciencepsychiatrymental disorders;
60.Injection of Anti-proBDNF Attenuates Hippocampal-Dependent Learning and Memory Dysfunction in Mice With Sepsis-Associated Encephalopathy

机译：抗议者注射抗脓毒症相关性脑病的小鼠中依赖于小鼠的海马依赖学习和内存功能障碍
- 作者：Yan-Hui Cui;Shi-Fen Zhou;Yu Liu;Shuang Wang;Fang Li;Ru-Ping Dai;Zhao-Lan Hu;Chang-Qi Li
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- sepsis associated encephalopathyproBDNFp75NTRhippocampuscognition and memory dysfunction;
61.Co-Ultramicronized Palmitoylethanolamide/Luteolin-Induced Oligodendrocyte Precursor Cell Differentiation is Associated With Tyro3 Receptor Upregulation

机译：共超大棕榈酰乙醇酰胺/叶黄素诱导的少突胶质细胞前体细胞分化与Tyro3受体上调有关
- 作者：Laura Facci;Massimo Barbierato;Mariella Fusco;Pietro Giusti;Morena Zusso
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- oligodendrocyte progenitor cellsTAM receptorsMBPCNPasePeaLut;
62.Endothelial Regulation by Exogenous Annexin A1 in Inflammatory Response and BBB Integrity Following Traumatic Brain Injury

机译：在创伤性脑损伤后炎症反应和BBB完整性的外源附睾A1内皮调节
- 作者：Han Liu;Junchi He;Yue Wu;Yang Du;Yinghua Jiang;Chengzhi Chen;Zhanyang Yu;Jianjun Zhong;Zhigang Wang;Chongjie Cheng;Xiaochuan Sun;Zhijian Huang
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- annexin A1blood–brain barrierinflammationRhoAtraumatic brain injury;
63.Plasma Lysophosphatidylcholine and Lysophosphatidylethanolamine Levels Were Associated With the Therapeutic Response to Olanzapine in Female Antipsychotics-na?ve First-episode Patients With Schizophrenia

机译：血浆溶血磷脂酰胆碱和溶血磷脂酰乙醇胺水平与乳腺嘌呤在雌性抗精神病药患者中对奥氮平的治疗反应有关的是精神分裂症患者
- 作者：Jiahong Liu;Meihong Xiu;Haixia Liu;Jun Wang;Xirong Li
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- schizophrenialysophospolipidtherapeutic responseolanzapineassociation;
64.The Pathology of Morphine-Inhibited Nerve Repair and Morphine-Induced Nerve Damage Is Mediated via Endoplasmic Reticulum Stress

机译：通过内质网胁迫介导吗啡抑制神经修复和吗啡诱导的神经损伤的病理学
- 作者：Jie Liu;Shanyong Yi;Weibo Shi;Guozhong Zhang;Songjun Wang;Qian Qi;Bin Cong;Yingmin Li
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- morphine dependenceacute morphine exposurecortexERSKi67NURR1;
65.Perampanel Reduces Hyperthermia-Induced Seizures in Dravet Syndrome Mouse Model

机译：Perampanel在Dravet综合征小鼠模型中减少了热疗诱导的癫痫发作
- 作者：Shih-Yin Ho;Li Lin;I-Chun Chen;Che-Wen Tsai;Fang-Chia Chang;Horng-Huei Liou
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- epilepsySCN1Astiripentolvalproic acidphenytoinNBQX;
66.Ginkgolide With Intravenous Alteplase Thrombolysis in Acute Ischemic Stroke Improving Neurological Function: A Multicenter, Cluster-Randomized Trial (GIANT)

机译：急性缺血性卒中中静脉内普罗基丙醇溶栓治疗神经功能：多中心，簇随机试验（巨头）
- 作者：Xuting Zhang;Wansi Zhong;Xiaodong Ma;Xiaoling Zhang;Hongfang Chen;Zhimin Wang;Min Lou
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- Ginkgolide?strokeintravenous alteplaseprognosisimprove;
67.Ginsenoside Rb1 Produces Antidepressant-Like Effects in a Chronic Social Defeat Stress Model of Depression Through the BDNF–Trkb Signaling Pathway

机译：人参皂甙RB1通过BDNF-TRKB信号通路在慢性社会失败压力模型中产生抗抑郁药物的效果
- 作者：Ning Jiang;Hong Huang;Yiwen Zhang;Jingwei Lv;Qiong Wang;Qinghu He;Xinmin Liu
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- ginsenoside Rb1depressionCSDSBDNFneurogenesismice;
68.Comparative Proteomic Characterization of Ventral Hippocampus in Susceptible and Resilient Rats Subjected to Chronic Unpredictable Stress

机译：患有慢性不可预测应力的敏感和弹性大鼠腹侧海马的比较蛋白质组织
- 作者：Yani Zhang;Xiaoling Zhang;Nuo Liu;Siyu Ren;Congyuan Xia;Xiong Yang;Yuxia Lou;Huiqin Wang;Ningning Zhang;Xu Yan;Zhao Zhang;Yi Zhang;Zhenzhen Wang;Naihong Chen
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- chronic unpredictable stressdepressionlabel-free quantitative proteomicsstress-resilientstress-susceptible;
69.The Heat Sensing Trpv1 Receptor Is Not a Viable Anticonvulsant Drug Target in the Scn1a+/? Mouse Model of Dravet Syndrome

机译：热敏Trpv1受体在SCN1A + /中不是一种可行的抗惊厥药物靶标。 Dravet综合征的小鼠模型
- 作者：Vaishali Satpute Janve;Lyndsey L.Anderson;Dilara Bahceci;Nicole A.Hawkins;Jennifer A.Kearney;Jonathon C.Arnold
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- SB-705498epilepsyseizuresepileptic encephalopathiesSCN1A geneCannabidiol (CBD)dravet syndrome (SMEI)the transient receptor potential vanilloid 1;
70.Phillyrin Prevents Neuroinflammation-Induced Blood–Brain Barrier Damage Following Traumatic Brain Injury via Altering Microglial Polarization

机译：通过改变微胶质偏振，预防创伤性脑损伤后，Phillyrin诱导神经炎炎症诱导的血脑屏障损伤
- 作者：Qian Jiang;Ding Wei;Xuejun He;Chao Gan;Xiaobing Long;Huaqiu Zhang
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- traumatic brain injuryphillyrinmicrogliaPPARγneuroinflammationblood–brain barrier;
71.Nicotine Increases Spontaneous Glutamate Release in the Rostromedial Tegmental Nucleus

机译：尼古丁增加了在rostromedial tegmental核中的自发谷氨酸释放
- 作者：Diego Castillo-Rolón;Enrique Ramírez-Sánchez;Gabina Arenas-López;Julieta Gardu?o;Omar Hernández-González;Stefan Mihailescu;Salvador Hernández-López
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- nicotineglutamatesynaptic releasecalcium imagingneuronal excitability;
72.Impact of Morphine Dependence and Withdrawal on the Reinforcing Effectiveness of Fentanyl, Cocaine, and Methamphetamine in Rats

机译：吗啡依赖性和戒断对大鼠芬太尼，可卡因和甲基甲基甲基甲基丙酮的增强效果
- 作者：Robert W.Seaman Jr;Gregory T.Collins
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- withdrawalpolysubstance abuseopioidsstimulantsprogressive ratio;
73.Optimal Course of Statins for Patients With Aneurysmal Subarachnoid Hemorrhage: Is Longer Treatment Better? A Meta-Analysis of Randomized Controlled Trials

机译：动脉瘤蛛网膜下腔患者的他汀类药物最佳过程：更好的治疗方法更好吗？随机对照试验的荟萃分析
- 作者：Tao Liu;Shiyu Zhong;Qingqing Zhai;Xudong Zhang;Huiquan Jing;Kunhang Li;Shengyu Liu;Shuo Han;Lishuai Li;Xin Shi;Yijun Bao
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- statinsaneurysmalsubarachnoid hemorrhageoutcomecomplicationsmeta-analysis;
74.Targeting Neuroinflammation in Brain Cancer: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical Developments

机译：靶向脑癌中的神经炎炎症：揭示机制，药理靶标和神经药物发育
- 作者：Mahmoud S.Alghamri;Brandon L.McClellan;Margaret S.Hartlage;Santiago Haase;Syed Mohd Faisal;Rohit Thalla;Ali Dabaja;Kaushik Banerjee;Stephen V.Carney;Anzar A.Mujeeb;Michael R.Olin;James J.Moon;Anna Schwendeman;Pedro R.Lowenstein;Maria G.Castro
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- immunosuppressioninflammationtumor microenvironmentgliomaimmunotherapy;
75.Inflammation Disturbed the Tryptophan Catabolites in Hippocampus of Post-operative Fatigue Syndrome Rats via Indoleamine 2,3-Dioxygenas Enzyme and the Improvement Effect of Ginsenoside Rb1

机译：炎症扰乱了通过吲哚胺2,3-二恶英酶的术后疲劳综合征大鼠的海马中的色氨酸分解代谢物和人参皂苷RB1的改善效果
- 作者：Shu Liu;Yue Cheng;Wei-Zhe Chen;Jin-Xiao Lv;Bei-Shi Zheng;Dong-Dong Huang;Xu-Fen Xia;Zhen Yu
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- post-operative fatigue syndromeinflammatory cytokinep38MAPKNF-κB/p65IDOginsenoside Rb1;
76.SC75741, A Novel c-Abl Inhibitor, Promotes the Clearance of TDP25 Aggregates via ATG5-Dependent Autophagy Pathway

机译：SC75741，一种新型C-ABL抑制剂，促进TDP25聚集体通过ATG5依赖性自噬途径的间隙
- 作者：Dongheng Zhou;Huanhuan Yan;Shuying Yang;Yuhong Zhang;Xiaoyan Xu;Xufeng Cen;Kai Lei;Hongguang Xia
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- autophagySC75741TDP43TDP25c-AblALSTFEB;
77.Enhancement of Insulin/PI3K/Akt Signaling Pathway and Modulation of Gut Microbiome by Probiotics Fermentation Technology, a Kefir Grain Product, in Sporadic Alzheimer’s Disease Model in Mice

机译：胰岛素发酵技术（Kefir Grave Maprody）在小鼠孢子族阿尔茨海默病模型中提高胰岛素/ PI3K / AKT信号通路和肠道微生物组的调节
- 作者：Nesrine S.El Sayed;Esraa A.Kandil;Mamdooh H.Ghoneum
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- metabolic syndromeinsulin signalingalzheimer's diseasePI3/Akt pathwayPFT;
78.Agmatine Alleviates Epileptic Seizures and Hippocampal Neuronal Damage by Inhibiting Gasdermin D-Mediated Pyroptosis

机译：Agmatine通过抑制燃气蛋白D介导的糊酶来减轻癫痫发作和海马神经元损伤
- 作者：Xueying Li;Jiahe Lin;Yingjie Hua;Jiaoni Gong;Siqi Ding;Yanru Du;Xinshi Wang;Rongyuan Zheng;Huiqin Xu
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- epilepsyagmatinepyroptosisinflammationGSDMD;
79.Quercetin-Conjugated Superparamagnetic Iron Oxide Nanoparticles Protect AlCl3-Induced Neurotoxicity in a Rat Model of Alzheimer’s Disease via Antioxidant Genes, APP Gene, and miRNA-101

机译：槲皮素共轭超顺磁性氧化铁纳米粒子通过抗氧化基因，APP基因和miRNA-101保护AlCl3诱导的阿尔茨海默病大鼠模型中的神经毒性
- 作者：Elnaz Amanzadeh Jajin;Abolghasem Esmaeili;Soheila Rahgozar;Maryam Noorbakhshnia
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- Alzheimer’s diseaseAlCl3quercetinmiR-101superparamagnetic iron oxide nanoparticleantioxidant;
80.Rivaroxaban Modulates TLR4/Myd88/NF-Kβ Signaling Pathway in a Dose-Dependent Manner With Suppression of Oxidative Stress and Inflammation in an Experimental Model of Depression

机译：Rivaroxaban以剂量依赖性方式调节TLR4 / MyD88 / NF-Kβ信号传导途径，抑制抑制抑郁症实验模型中的氧化应激和炎症
- 作者：Walaa Yehia Abdelzaher;Hanaa H.Mohammed;Nermeen N.Welson;Gaber El-Saber Batiha;Roua S.Baty;Asmaa Mohamed Abdel-Aziz
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- depressionMyD88NF-kβrivaroxbanTLR4;
81.Exogenous Carbon Monoxide Produces Rapid Antidepressant- and Anxiolytic-Like Effects

机译：外源一氧化碳产生快速的抗抑郁药和抗焦虑效果
- 作者：Yixiao Luo;Rafi Ullah;Jinfeng Wang;Yuru Du;Shihao Huang;Li Meng;Yuan Gao;Miao Gong;Ewa Galaj;Xi Yin;Haishui Shi
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- carbon monoxideheme oxygenase-1depressionanxietyinflammation;
82.Berberine Attenuates Cerebral Ischemia-Reperfusion Injury Induced Neuronal Apoptosis by Down-Regulating the CNPY2 Signaling Pathway

机译：小檗碱通过降低CNPy2信号通路，衰减脑缺血再灌注损伤诱导的神经元细胞凋亡
- 作者：Lina Zhao;Huanming Li;Qian Gao;Jin Xu;Yongjie Zhu;Meili Zhai;Peijun Zhang;Na Shen;Yanbo Di;Jinhui Wang;Tie Chen;Meina Huang;Jinglai Sun;Chong Liu
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- berberinecerebral ischemia-reperfusion injuryapoptosisCNPY2pathway;
83.Analysis of M4 Transmembrane Segments in NMDA Receptor Function: A Negative Allosteric Modulatory Site at the GluN1 M4 is Determining the Efficiency of Neurosteroid Modulation

机译：NMDA受体功能中M4跨膜段的分析：GLUN1 M4处的负变质调节位点确定神经活体调制效率
- 作者：Kai Langer;Adriana Müller-L?ngle;Jannik Wempe;Bodo Laube
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- N-methyl-D-aspartate receptorexcitatory glycine receptorM4transmembrane segment interactionspregnenolone sulfatenegative allosteric modulator;
84.Neuroprotective and Angiogenesis Effects of Levetiracetam Following Ischemic Stroke in Rats

机译：Levetiracetam在大鼠缺血性脑卒中后Nevetiracetam的神经保护和血管生成效应
- 作者：Xiang Yao;Wenping Yang;Zhendong Ren;Haoran Zhang;Dafa Shi;Yanfei Li;Ziyang Yu;Qiu Guo;Guangwei Yang;Yingjiang Gu;Hairong Zhao;Ke Ren
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- ischemic strokelevetiracetamneuroprotectionhypoxia-inducible factorheat shock protein 70vascular endothelial growth factor;
85.Edaravone Plays Protective Effects on LPS-Induced Microglia by Switching M1/M2 Phenotypes and Regulating NLRP3 Inflammasome Activation

机译：埃德拉武酮通过切换M1 / M2表型对LPS诱导的小胶质细胞进行保护作用，并调节NLRP3炎症组件
- 作者：Jiping Li;Xinping Dai;Liuyi zhou;Xinxiu Li;Dongxiao Pan
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- parkinson’s diseasemicrogliainflammasomeedaravonepolarization;
86.Identification of Critical Residues in the Carboxy Terminus of the Dopamine Transporter Involved in the G Protein βγ-Induced Dopamine Efflux

机译：鉴定参与G蛋白βγ诱导的多巴胺流出的多巴胺转运蛋白末端的关键残留物
- 作者：José A.Pino;Gabriel Nu?ez-Vivanco;Gabriela Hidalgo;Miguel Reyes Parada;Habibeh Khoshbouei;Gonzalo E.Torres
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- dopaminedopamine transportereffluxamphetamineg-protein βγ;
87.Prolonged Withdrawal From Escalated Oxycodone Is Associated With Increased Expression of Glutamate Receptors in the Rat Hippocampus

机译：升级的羟考酮延长戒断与大鼠海马谷氨酸受体的表达增加有关
- 作者：Aaron J.Salisbury;Christopher A.Blackwood;Jean Lud Cadet
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- hippocampusincubation of drug cravingNMDA receptorAMPA receptoropioid use disordermetabotropic glutamate receptor;
88.Individual Traits and Pain Treatment: The Case of Hypnotizability

机译：单独的特质和疼痛治疗：催眠术的情况
- 作者：Enrica Laura Santarcangelo;Giancarlo Carli
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- hypnotic susceptibilitycognitive pain controlsuggestionsanalgesiaimageryautonomicimmune systemcortical plasticity;
89.Empagliflozin Effectively Attenuates Olanzapine-Induced Body Weight Gain in Female Wistar Rats

机译：Empagliflozin有效地衰减了女性Wistar大鼠的奥氮翼诱导的体重增加
- 作者：Ghulam Md Ashraf;Badrah S.Alghamdi;Fahad S.Alshehri;Mohammad Zubair Alam;Haythum O.Tayeb;Frank I.Tarazi
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- antidiabeticsantipsychoticsbody weight gainempagliflozinolanzapinewistar ratsgender difference;
90.Curcumin Exerts Antinociceptive Effects in Cancer-Induced Bone Pain via an Endogenous Opioid Mechanism

机译：姜黄素通过内源性阿片类机制施用癌症诱导的骨疼痛
- 作者：Guanghai Zhao;Yongqiang Shi;Chaoyang Gong;Taicong Liu;Wei Nan;Lin Ma;Zuolong Wu;Chaoming Da;Kaisheng Zhou;Haihong Zhang
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- curcuminantinociceptioncancer-induced bone painendogenous opioid peptidesmechanism;
91.Chinese Herbal Medicine for Treating Epilepsy

机译：中国草药治疗癫痫
- 作者：Chia-Hui Lin;Ching-Liang Hsieh
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- Chinese herbal medicineepileptic seizureantiepileptic effectcomplementary therapydiet therapy;
92.Anti-PTSD Effects of Hypidone Hydrochloride (YL-0919): A Novel Combined Selective 5-HT Reuptake Inhibitor/5-HT1A Receptor Partial Agonist/5-HT6 Receptor Full Agonist

机译：盐酸克隆酮的抗病毒术（YL-0919）：一种新型组合选择性5-HT再摄取抑制剂/ 5-HT1A受体部分激动剂/ 5-HT6受体全激动剂
- 作者：Wen-Gang Liu;Li-Ming Zhang;Jun-Qi Yao;Yong-Yu Yin;Xiao-Ying Zhang;Yun-Feng Li;Jiang-Bei Cao
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- hypidone hydrochloride (YL-0919)posttraumatic stress disordercognition impairmentbrain-derived neurotrophic factorneuroplasticity;
93.Gestational Folic Acid Administration Alleviated Maternal Postpartum Emotional and Cognitive Dysfunction in Mice

机译：妊娠叶酸给药缓解了小鼠的母体产后情绪和认知功能障碍
- 作者：Qianyu Zhang;Qianwen Huang;Li Yao;Wenjuan Liu;Jianxing Ruan;Yingqi Nong;Ye Chen;Lin Fan;Jinyan Wei;Songlu Wang;Li Sun;Hao Li;Yan Zhang;Xiqian Zhang;Fenghua Liu
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- folic acidpostpartumbehaviorhippocampusbrain-derived neurotrophic factor;
94.Erythropoietin Produces a Dual Effect on Carotid Body Chemoreception in Male Rats

机译：促红细胞生成素对雄性大鼠的颈动脉体化学意义产生了双重影响
- 作者：Christian Arias-Reyes;Sofien Laouafa;Natalia Zubieta-DeUrioste;Vincent Joseph;Aida Bairam;Edith M.Schneider Gasser;Jorge Soliz
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- chemosensinghypoxiahypercapnianitric oxideelectrophysiology;
95.Dexmedetomidine and Netrin-1 Combination Therapy Inhibits Endoplasmic Reticulum Stress by Regulating the ERK5/MEF2A Pathway to Attenuate Cerebral Ischemia Injury

机译：Dexmedetomidine和Netrin-1组合疗法通过调节ERK5 / MEF2A途径来抑制脑缺血损伤来抑制内质网胁迫
- 作者：Jiang-Wen Yin;Jia Li;Yi-Min Ren;Yan Li;Rui-Xue Wang;Sheng Wang;Yun-Xia Zuo
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- dexmedetomidineNetrin-1endoplasmic reticulum stresscerebral ischemia/reperfusionoxygen-glucose deprivationapoptosis;
96.Amphetamine Promotes Cortical Up State in Part Via Dopamine Receptors

机译：Amphetamine部分通过多巴胺受体促进皮质升压状态
- 作者：Guofang Shen;Wei-Xing Shi
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- amphetamineprefrontal cortexUp stateslow oscillationdopaminenorepinepherinecortical stateattention;
97.Novel Antimicrobial Treatment Strategy Based on Drug Delivery Systems for Acute Otitis Media

机译：基于急性中耳炎药物递送系统的新型抗菌治疗策略
- 作者：Masamitsu Kono;Nafisa K.Umar;Saori Takeda;Makiko Ohtani;Daichi Murakami;Hideki Sakatani;Fumie Kaneko;Denisa Nanushaj;Muneki Hotomi
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- acute otitis mediadrug delivery systemPK/PDsustained releaseantibiotics;
98.Salmon Calcitonin Attenuates Some Behavioural Responses to Nicotine in Male Mice

机译：鲑鱼降钙素衰减对雄性小鼠的尼古丁的一些行为反应
- 作者：Cajsa Aran?s;Jesper Vestlund;Sarah Witley;Christian E.Edvardsson;Aimilia Lydia Kalafateli;Elisabet Jerlhag
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- appetite-regulatory hormonesamylin receptorscalcitonin receptorsrewardpharmacological treatments;
99.Neurons in the Locus Coeruleus Modulate the Hedonic Effects of Sub-Anesthetic Dose of Propofol

机译：遗迹中的神经元调节亚毒性剂量的异丙酚的蜂窝效果
- 作者：Hui Chen;Dan Xu;Yu Zhang;Yan Yan;JunXiao Liu;ChengXi Liu;Wei Shen;Tian Yu;Jin Liu
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- propofolhedoniclocus ceruleusventral tegmental areachemogeneticfiber photometry;
100.PPAR γ Prevents Neuropathic Pain by Down-Regulating CX3CR1 and Attenuating M1 Activation of Microglia in the Spinal Cord of Rats Using a Sciatic Chronic Constriction Injury Model

机译：PPARγ通过坐标慢性收缩损伤模型通过下调节CX3CR1并通过曲线慢性收缩损伤模型衰减大鼠脊髓中微胶质细胞的M1活化的神经疗法
- 作者：Xilei Li;Qulian Guo;Zhi Ye;E.Wang;Wangyuan Zou;Zhihua Sun;Zhenghua He;Tao Zhong;Yingqi Weng;Yundan Pan
- 期刊名称：《Frontiers in Neuropharmacology》 | 2021年第a期
- PPAR γmicroglianeuropathic painCX3CR1neuroinflammation;

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