Rate Dependent Deformation Response of Articular Cartilage

摘要

Osteoarthritis (OA) is a leading cause of severe disability in the United States. OA is characterized by the failure of articular cartilage, which in many cases provides a low friction, low wear interface in the body's joints over decades of use. Many researchers have shown that cartilage's load bearing and lubrication properties can be attributed to its biphasic structure. Interstitial fluid pressure can carry a substantial portion of the contact force, and the friction coefficient is linearly proportional to the portion of the load supported by the elastic matrix.