Anti-haptoglobin antibody detection after febrile non-hemolytic transfusion reactions in a non-haptoglobin-deficient patient.

摘要

Non-hemolytic reactions are common adverse transfusion-associated events, and febrile episodes have been defined as febrile non-hemolytic transfusion reactions (FNHTR) (1). Leukoagglutinins of recipients or donors are believed to be the primary cause of many of these febrile reactions [1]. Recently, pre-storage white blood cell reduction was found to reduce the number of FNHTR from 0.45% to 0.11% [2]. We describe herein a patient with FNHTR after the transfusion of leukoreduced single-donor apheresis platelet concentrates (LR-PC).