High-Throughput Method for the Quantification of Lacosamide in Serum Using Ultrafast SPE-MS/MS

摘要

Background: Lacosamide is an anticonvulsant drug approved for adjunctive therapy of partial-onset seizures in adults. Monitoring serum lacosamide concentrations may be useful in assessing compliance and optimizing therapy. The clinical need for faster turn-aroundtimes and increased testing volumes has led to the desire to develop faster methods of analysis for higher throughput of samples.