Long-term Results of Endoscopic Sinus Surgery-Oriented Treatment for Chronic Rhinosinusitis With Asthma

摘要

Objectives/Hypothesis: The aims of this study were to evaluate the efficacy of functional endoscopic sinus surgery (FESS)-oriented multimodality treatment in chronic rhinosinusitis (CRS) patients with asthma and its impact on asthma.Study Design: Prospective, nonrandomized cohort.Methods: Twenty-seven CRS patients with asthma who underwent FESS with postoperative topical corticosteroid spray were evaluated preoperatively; 25 of them were evaluated 1 year and 3 years postoperatively CRS was evaluated by visual analogue scale, clinical control of CRS, and objective measurement endoscopy Lund-Kennedy scores. Asthma was assessed by subjective asthma control test and asthma control level, also by objective antiasthma medication use and pulmonary function tests.Results: VAS scores of general symptoms (8.09 +- 0.87 preoperatively) were significantly improved at 1 year (2.94 +- 2.21) and 3 years (3.77 +- 2.16) postoperation (P = .000). No difference in these items was found between 1 year and 3 years (P=,463). Endoscopy Lund-Kennedy scores at 1 year (4.34 +- 3.09) and 3 years (5.80 +- 3.38) postoperatively were significantly better (9.33 +- 2.03 preoperatively P = .000), and there was no difference between 1 year and 3 years of follow-up (P>.05). Significantly, asthma control level improved postoperatively (P = .025). However, antiasthma drug and pulmonary function showed no significant change postoperatively (P>.05).Conclusions: FESS-oriented multimodality treatment improves CRS with asthma significantly and persistently. Asthma control level improved. Antiasthma medication use and pulmonary function remained stable.