Our brain is a network. On a macroscopic level, hundreds of brain regions, each having their own task or function, interact through thousands of structural connections, continuously processing, sharing, and integrating information.Driven by advances in neuroimaging techniques and mathematics, it has now become increasingly feasible to examine large scale brain connectivity, both structurally and functionally (1). Structural connectivity refers to the physical connections between brain regions, such as white matter pathways; functional connectivity refers to the level of statistical dependence between activation patterns of brain regions, often believed to reflect, to some extent, large-scale neuronal communication. High levels of efficient functional and structural brain connectivity are known to be crucial for healthy performance of the brain (2). Conversely, one may expect abnormalities in connectivity of the brain to relate to psychiatric illnesses, such as schizophrenia.
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