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首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Cervical insufficiency: re-evaluating the prophylactic cervical cerclage.
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Cervical insufficiency: re-evaluating the prophylactic cervical cerclage.

机译:宫颈机能不全:重新评估预防性宫颈环扎。

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Historically, placement of a cervical cerclage was based almost entirely on the obstetrical history. Over the past two decades however, we have recognised that history alone may not be the only indication for cerclage but rather, complementing the obstetrical history with ultrasonographic and biochemical findings may better identify those women who may benefit most from the placement of a cervical cerclage. Review of the literature appears to suggest that the best approach towards the management of a cervical insufficiency is to first categorise women as being either high risk of low risk-based on obstetrical history. Although women with an obstetrical history of at least three 2nd trimester losses are likely to benefit from a prophylactic cerclage than those without this history may better be managed with progesterone and serial cervical length measurements. This approach can in turn be used to identify those women with early cervical shortening that may require an emergency cerclage. Although randomised controlled trials are still lacking, recent studies suggests that this approach may be more effective especially when combined with markers of intra-amniotic inflammation. As for the prophylactic cerclage itself, with the abdominal cerclage being less invasive given the possibility of a laparoscopic placement, it may prove to be a more effective alternative to the conventionally placed McDonald cerclage. This however, remains to be evaluated more carefully.
机译:从历史上看,宫颈环扎的放置几乎完全基于产科史。然而,在过去的二十年中,我们已经认识到,仅凭病史可能不是唯一的环扎指示,而是用超声检查和生化检查结果对产科病史进行补充可以更好地识别出那些可能从宫颈环扎术中受益最大的女性。对文献的审查似乎表明,应对宫颈机能不全的最佳方法是首先根据产科历史将妇女归为高风险或低风险。尽管具有产科病史至少三分之二的妇女比起没有此病史的妇女可能受益于预防性环扎术,但最好通过孕激素和连续宫颈长度测量来处理。反过来,该方法可用于识别那些可能需要紧急环扎的早期宫颈缩短的女性。尽管仍然缺乏随机对照试验,但最近的研究表明,这种方法可能更有效,尤其是与羊膜内炎症标记物结合使用时。至于预防性环扎本身,考虑到腹腔镜放置的可能性,腹部环扎的侵入性较小,它可能被证明是常规放置的麦当劳环扎的一种更有效的替代方法。但是,这有待更仔细地评估。

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