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Probiotics: a proactive approach to health. A symposium report

机译:益生菌:积极主动的健康方法。专题报告

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This report summarises talks given at the 8th International Yakult Symposium, held on 23-24 April 2015 in Berlin. Two presentations explored different aspects of probiotic intervention: the small intestine as a probiotic target and inclusion of probiotics into integrative approaches to gastroenterology. Probiotic recommendations in gastroenterology guidelines and current data on probiotic efficacy in paediatric patients were reviewed. Updates were given on probiotic and gut microbiota research in obesity and obesity-related diseases, the gut-brain axis and development of psychobiotics, and the protective effects of equol-producing strains for prostate cancer. Recent studies were presented on probiotic benefit for antibiotic-associated diarrhoea and people with HIV, as well as protection against the adverse effects of a short-term high-fat diet. Aspects of probiotic mechanisms of activity were discussed, including immunomodulatory mechanisms and metabolite effects, the anti-inflammatory properties of Faecalibacterium prausnitzii, the relationship between periodontitis, microbial production of butyrate in the oral cavity and ageing, and the pathogenic mechanisms of Campylobacter. Finally, an insight was given on a recent expert meeting, which re-examined the probiotic definition, advised on the appropriate use and scope of the term and outlined different probiotic categories and the prevalence of different mechanisms of activity.
机译:本报告总结了2015年4月23日至24日在柏林举行的第八届国际养乐多研讨会的演讲。有两个演示文稿探讨了益生菌干预的不同方面:作为益生菌靶标的小肠和将益生菌纳入胃肠病学的综合方法。审查了胃肠病学指南中的益生菌建议以及有关儿科患者益生菌功效的最新数据。给出了有关肥胖和与肥胖相关疾病的益生菌和肠道菌群研究,肠脑轴和精神药物的发展以及产生雌马酚的菌株对前列腺癌的保护作用的最新信息。最近的研究提出了益生菌对抗生素相关性腹泻和艾滋病毒感染者的益处,以及针对短期高脂饮食的不利影响的保护措施。益生菌的活动机制的方面进行了讨论,包括免疫调节机制和代谢产物的作用,普氏不动杆菌的抗炎特性,牙周炎,口腔中丁酸的微生物产生与衰老之间的关系以及弯曲杆菌的致病机制。最后,在最近的一次专家会议上给出了见解,该会议重新审查了益生菌的定义,为该术语的适当用法和范围提供了建议,并概述了不同的益生菌类别和不同活动机制的普遍性。

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