首页> 外文期刊>The British Journal of Nutrition >Effects of yeast cell walls on performance and immune responses of cyclosporine A-treated, immunosuppressed broiler chickens.
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Effects of yeast cell walls on performance and immune responses of cyclosporine A-treated, immunosuppressed broiler chickens.

机译:酵母细胞壁对环孢霉素A处理,免疫抑制的肉鸡的生产性能和免疫反应的影响。

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The present study was conducted to investigate the effects of dietary yeast (Saccharomyces cerevisiae) cell walls (YCW) from the yeast extract industry on performance and immune function of cyclosporine A (CSA)-treated, immunosuppressed broiler chickens. A total of 240 day-old male broilers were allocated randomly into four treatments: (1) non-challenged control; (2) non-challenged control+0.3% YCW; (3) CSA-challenged group; (4) CSA-challenged+0.3% YCW. On days 1-4 and 22-25 of age, broilers were subcutaneously injected with CSA or sterile saline. The results showed that supplementation of YCW significantly improved daily weight gain (DWG) during the starter (days 1-21, P<0.01), finisher (days 22-42, P<0.01) and overall (days 1-42, P<0.05) periods compared with the control birds, but had no effect on feed conversion ratio (FCR, P
机译:进行本研究以研究酵母提取物行业的日粮酵母(Saccharomyces cerevisiae)细胞壁(YSW)对经环孢霉素A(CSA)处理,免疫抑制的肉鸡的性能和免疫功能的影响。总共将240只日龄雄性肉鸡随机分为4种处理方法:(1)非挑战性对照; (2)非挑战控制权+ 0.3%YCW; (3)CSA挑战小组; (4)CSA挑战了+ 0.3%的YCW。在年龄1-4和22-25天,给肉鸡皮下注射CSA或无菌盐水。结果表明,补充YCW可以显着改善开胃菜(1-21天, P <0.01),肥育期(22-42天, P 0.01)和整个(1-42天, P <0.05)时期,但对饲料转化率(FCR, P <0.01)和FCR升高( P <0.05)。累积地在第21天和第42天,YCW减轻了CSA诱导的外周血淋巴细胞成胚反应的降低( P <0.01)。此外,YCW改善了Fabricius( P <0.01)和胸腺( P <0.01)滑囊的相对重量,并上调了促炎性脾脏的表达与经CSA处理的禽类相比,第42天的细胞因子IL-1β( P <0.01)和IL-6( P <0.01)。这些结果表明,补充YCW在减轻CSA攻击的免疫抑制作用方面具有有益作用,从而改善了肉鸡的生长性能。

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