Diagnosis of Aspergillus niger peritonitis in a peritoneal dialysis patient by peritoneal galactomannan and β-D-glucan detection.

摘要

Fungus is an uncommon cause of peritonitis in continuous ambulatory peritoneal dialysis (CAPD). Fungal CAPD-related peritonitis has been associated with high mortality (22% - 33%) and a high rate of CAPD discontinuation (50% - 85%) (1). Here, we report a case of Aspergillus niger peritonitis that was diagnosed in a female patient on CAPD through the detection of (3-D-glucan (BDG) and galactomannan (GM) positivityin peritonealfluid and plasma. The patient was successfully treated with intravenous amphotericin B and removal of the peritoneal catheter. To our knowledge, this is the first report of peritonealfluid GM and BDG detection being used for diagnosis in this setting.