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Allergic Rhinitis and Intranasal Corticosteroid Sprays

机译:过敏性鼻炎和鼻内糖皮质激素喷雾剂

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摘要

Management of AR usually begins in the pharmacy, with patients asking pharmacists for recommendations. It is important for pharmacists to have an understanding of AR and the various options available to prevent and treat this condition.AR is a chronic inflammatory disease affecting the upper . airways. This inflammation of the nasal mucosal lining is a result of inhaled aeroallergens, which the patient has been previously sensitized to, binding to immunoglobulin E (IgE) on the surface of mast cells, leading to mast cell degranulation and release of preformed mediators, such as histamine and leukotrienes.
机译:AR的管理通常始于药房,患者会向药剂师寻求建议。对药剂师来说,重要的是要了解AR及其预防和治疗这种病的各种选择。AR是一种慢性炎性疾病,影响了上肢。气道。鼻粘膜衬里的这种炎症是由于吸入的气态变应原引起的,患者先前已经敏化了该变应原,与肥大细胞表面的免疫球蛋白E(IgE)结合,导致肥大细胞脱粒并释放预先形成的介质,例如组胺和白三烯。

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