Francois Jacob, a Nobel-prizewinning French biologist, died on 19 April aged 92. With Jacques Monod and Andre Lwoff, Jacob shared the 1965 Nobel Prize in Physiology or Medicine for his work on gene expression and how it is controlled. While working at the Pasteur Institute in Paris, he identified regulatory proteins that bind to DNA, preventing its transcription into RNA and thus dampening the expression of cellular enzymes.
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