Aliphatic C-H Bond Oxidation of Toluene Using Copper Peroxo Complexes That Are Stable at Room Temperature

摘要

The interaction of copper(I) complexes with dioxygen has been studied intensively during the last 30 years with regard to the possible application of such compounds for the selective catalytic oxidation of organic substrates by air. Monooxygenases that contain copper ions in their active sites [e.g., tyrosinase or a-hydroxylating monooxygenase (PHM)] perform selective hy-droxylation reactions of organic substrates. Modeling the reactivity of these enzymes using low-molecular-weight copper complexes has attracted much attention.