Research Note: Acid-Adpated Listeria Monocytogenes DisplaysEnhanced Tolerance against the Lantibiotics Nisin and Lacticin 3147

摘要

Log-phase Listeria monocytogenes cells become tolerant to a variety of environmental stresses following acid adaptation at pH 5.5. We demonstrated that adapted cells also exhibit increased tolerance to nisin and, to a lesser extent, lacticin 3147. At nisin concentrations of 100 and 200 IU/ml the survival of acid-adapted cells was approximately 10-fold greater than Nonadapted cells. However, acid adaptation had only a moderate effect on the tolerance of L. Monocytogenes to lacticin 3147, A phenomenon that possibly reflects the distinct mode of action of this bacteriocin.