Surface-Enhanced Raman Scattering Substrate Fabricated by Femtosecond Laser Induced Co-deposition of Silver Nanoparticles and Fluorescent Molecules

摘要

Surface-enhanced Raman scattering (SERS) substrate with embedded molecules was fabricated by femtosecond laser induced co-deposition. During the femtosecond laser irradiation, silver ions in the AgNO_3 solution were reduced and co-deposited on the slip surface together with organic molecules as SERS substrates. Raman scattering of the embedded molecules at the interstices of nanoparticles was strongly enhanced due to the localized electromagnetic field and the fluorescence was partly quenched. The enhanced Raman/fluorescence ratio makes it possible to distinguish the Raman signal from fluorescence for fluorescent samples at a high concentration. The fabricated SERS substrate can be used for the detection of specific biomolecules with high sensitivity.