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High-Speed Magnetic Microrobot Actuation in a Microfluidic Chip by a Fine V-Groove Surface

机译:细V型槽表面在微流控芯片中高速磁控微型机器人致动

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Microrobots are promising tools for the treatment of biological cells because of their lack of skill dependence, high throughput, and high repeatability. Integration of a microfluidic chip and robotics based on microelectromechanical systems technology is a key challenge for biomedical innovations. In addition to the advantage of environmental control by a microfluidic chip, robots enable physical operations on the cell with high throughput. This paper presents high-speed microrobotic actuation driven by permanent magnets in a microfluidic chip. The developed microrobot has a milli-Newton-level output force from a permanent magnet, micrometer-level positioning accuracy, and drive speed of over 280?mm/s. The riblet surface, which is a regularly arrayed V-groove, reduces fluid friction and enables high-speed actuation. Ni and Si composite fabrication was employed to form the optimum riblet shape on the microrobot's surface by wet and dry etching. The evaluation experiments show that the microrobot can be actuated at a rate of up to 90?Hz, which is more than ten times higher than that of the microrobot without a riblet. Two distinguish applications of the developed microrobots were demonstrated in a microfluidic chip.
机译:微型机器人由于缺乏技术依赖性,高通量和高可重复性,是用于治疗生物细胞的有前途的工具。基于微机电系统技术的微流控芯片和机器人技术的集成是生物医学创新的关键挑战。除了通过微流控芯片进行环境控制的优势外,机器人还可以使细胞以高通量进行物理操作。本文提出了由微流体芯片中的永磁体驱动的高速微机器人致动。研发的微型机器人具有永久磁铁的毫牛顿级输出力,微米级定位精度,驱动速度超过280?mm / s。呈规则排列的V型槽的肋状表面可减少流体摩擦并实现高速驱动。通过湿法和干法刻蚀,采用Ni和Si复合制造工艺在微型机器人的表面上形成最佳的肋状形状。评估实验表明,微型机器人可以以高达90?Hz的速度启动,这比不带肋的微型机器人高出十倍以上。在微流控芯片中展示了已开发的微型机器人的两个独特应用。

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