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Immunological Assays for Mycotoxin Detection

机译:真菌毒素检测的免疫分析

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MYCOTOXINS ARE TOXIC S6C-ondary metabolites produced by molds that often contaminate agricultural staples such as corn, wheat, and peanuts prior to harvest and during storage. These compounds have a wide array of chemical structures and are produced by common field and storage fungi, including many species of Aspergillus, Peni-cillium, and Fusarium. Mycotoxins can elicit a variety of toxic symptoms in humans and animals, ranging from gastroenteritis to cancer (Table 1). For example, the aflatoxins were identified in the early 1960s as etiologic agents of hepatotoxicity and hepatic cancer in turkey poults and rainbow trout, respectively (Pestka and Casale, 1990). Strict regulations were subsequently established for aflatoxins in food in many countries because of the potential for similar effects in humans.
机译:霉菌毒素是由霉菌产生的有毒的S6C代谢产物,通常在收获前和储存期间会污染农作物的主食,例如玉米,小麦和花生。这些化合物具有广泛的化学结构,是由常见的田间和储藏真菌产生的,包括许多曲霉菌,青霉菌和镰刀菌。霉菌毒素可在人类和动物中引发各种毒性症状,从胃肠炎到癌症(表1)。例如,黄曲霉毒素在1960年代初被确定为火鸡家禽和虹鳟鱼肝毒性和肝癌的病原体(Pestka和Casale,1990)。随后在许多国家对食品中的黄曲霉毒素制定了严格的法规,因为它可能对人类产生类似的影响。

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