A Therapeutic Insight in β-Cell Imaging?

摘要

β-Cells are the core effector of glycemic control, and when largely lost in the course of type 1 diabetes, glycemic control is no longer guaranteed. Although glycemic control can be established by insulin injections, diabetic patients still suffer from microvascular (nephropathy, retinopathy, neuropathy) and macrovascular (ischemic heart disease, cerebrovascular disease, peripheral vascular disease) complications, resulting in a lower life expectancy (1). Therefore, islet transplantation has been implemented as one therapeutic means to achieve a more physiologic form of glycemic control.