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Neonatal Cerebral Abnormalities and Later Verbal and Visuospatial Working Memory Abilities of Children Born Very Preterm

机译:早产儿的新生儿脑异常和后来的言语和视觉空间工作记忆能力

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As part of a prospective, longitudinal study, 103 very preterm children underwent structural magnetic resonance (MR) imaging at term equivalent age and an assessment of verbal (Digit Span) and visuospatial (Corsi Blocks) working memory at 6 years corrected age. Compared to children born full term (N = 108), very preterm children were characterized by poorer verbal and visuospatial working memory performance. Very preterm children without cerebral abnormalities performed similarly to full-term children. Verbal impairments were largely confined to children with earlier moderate-severe cerebral abnormalities, while children with mild and moderate-severe abnormalities showed greater difficulties in visuospatial working memory. Findings suggest that very preterm children may be particularly vulnerable to visuospatial impairment. They also highlight the role of early neurological disturbance in the evolution of these difficulties.View full textDownload full textRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/87565641.2010.508669
机译:作为一项前瞻性纵向研究的一部分,对103名早产儿在足月等效年龄进行了结构磁共振(MR)成像,并在校正后的6岁时对言语(Digit Span)和视觉空间(Corsi Blocks)工作记忆进行了评估。与足月出生的孩子(N = 108)相比,早产儿的语言和视觉空间工作记忆性能较差。没有大脑异常的早产儿的表现与足月儿相似。言语障碍主要限于早期中度至重度脑部异常的儿童,而轻度和中度至重度脑异常的儿童在视觉空间工作记忆方面表现出更大的困难。研究结果表明,早产儿可能特别容易遭受视觉空间损伤。他们还强调了早期神经功能紊乱在这些困难演变过程中的作用。查看全文下载全文相关var addthis_config = {ui_cobrand:“泰勒和弗朗西斯在线”,servicescompact:“ citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook ,stumbleupon,digg,google,more“,发布号:” ra-4dff56cd6bb1830b“};添加到候选列表链接永久链接http://dx.doi.org/10.1080/87565641.2010.508669

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