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Analysis of the relationship between periodontitis and osteoporosis/fractures: a cross-sectional study

机译:牙周炎与骨质疏松症/裂缝关系的分析:横截面研究

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Chronic periodontitis is a multifactorial inflammatory disease resulting in patients exhibiting high levels of inflammatory factors causing systemic inflammatory bone destruction that may lead to osteoporosis development. The association between periodontitis and osteoporosis has been documented; however, the findings remain unclear. This study aimed to identify the association between periodontitis and osteoporosis using a cross-sectional study design and Korean Genome and Epidemiology Study (KoGES) health examinee data. This cross-sectional study used epidemiological data from the KoGES during 2004–2016. Of 125,324 participants (age, 40–79?years), 9969 with periodontitis and 115,332 controls (without periodontitis) were selected. We analyzed the history of osteoporosis and fractures of all participants. All participants were examined according to age, sex, income group, obesity, smoking habits, alcohol consumption, and food intake. To analyze the odds ratio (OR) of periodontitis for those with osteoporosis and fractures, a logistic regression model was used. The adjusted odds ratio (aOR) of periodontitis for osteoporosis was 2.16 (95% confidence interval [CI], 2.01–2.31; P??0.001). The aOR of periodontitis for any fracture was 1.54 (95% CI 1.46–1.62; P??0.001). Osteoporosis and fractures are associated with periodontitis. Performing regular oral hygiene and examinations of bone mineral density are recommended to prevent aggravation of osteoporosis and periodontitis.
机译:慢性牙周炎是一种多因素炎症疾病,导致患者表现出高水平的炎症因素,导致系统性炎症性骨质破坏,可能导致骨质疏松发展发育。牙周炎和骨质疏松症之间的关联已记录;但是,调查结果仍然不清楚。本研究旨在使用横截面研究设计和韩国基因组和流行病学研究(Koges)健康检测数据之间的牙周炎和骨质疏松症之间的关联。这种横断面研究在2004 - 2016年期间使用了Koges的流行病学数据。参加125,324名参与者(年龄,40-79岁),9969年,牙周炎和115,332次(没有牙周炎)。我们分析了所有参与者的骨质疏松症和骨折的历史。根据年龄,性别,收入小组,肥胖,吸烟习惯,酒精消费和食物摄入量检查所有参与者。为了分析骨质疏松症和骨折的那些牙周炎的牙周炎率(或),使用逻辑回归模型。骨质疏松症的牙周炎的调整后的差距(AOR)为2.16(95%置信区间[CI],2.01-2.31;p≤≤0.001)。任何骨折的牙周炎的AOR为1.54(95%CI 1.46-1.62;p≤≤0.001)。骨质疏松症和骨折与牙周炎有关。建议进行常规口服卫生和骨密度的检查,以防止骨质疏松症和牙周炎的加重。

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